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MVRBC SOP Changes. That will affect Client Hospitals October, 2011 TAC Meeting. Effective DATE . Monday, September 19 th. Antibody Screens. All antibody ID samples will receive a Room Temperature 30 minute antibody screen
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MVRBC SOP Changes That will affect Client Hospitals October, 2011 TAC Meeting
Effective DATE Monday, September 19th
Antibody Screens • All antibody ID samples will receive a Room Temperature 30 minute antibody screen • Performed to catch any cold reactive antibodies including autoantibodies • All antibody ID samples will receive a screen with PeG or LISS in addition to the RT screen. • Allows us to view another perspective on antibody reactivity. • Not all antibodies will react with every method.
Antibody Identification • Techs will be testing FULL 10-11 cell panels on patients with previously identified antibodies. • Prior practice was to choose selected cells to rule in antibody with one cell and choose cells to rule out other clinically significant antibodies. • Will allow MVRBC to better provide for client hospitals by testing with complete panels. • Minimizes chances that an antibody will be missed, such as an antibody to a low frequency antigen.
DAT / Elution Testing • All Antibody ID Samples will receive a DAT • MVRBC wants to meet our patient’s need by providing the most complete workup • All positive DAT / AHG positive autocontrols will have an eluate performed regardless of the transfusion history • Prior practice was to perform an eluate if the patient has been transfused within the last three months. • Can be a safety issue – How accurate is the transfusion history we receive? Have they been treated at another hospital we don’t know about?
Absorption on Eluates • Eluates will only be adsorbed if the patient has been transfused within 21 days • Prior process was to absorb if the patient had been transfused within 3 months. • TM 16th ed. States that an antibody will typically be produced by 14-21 days after transfusion at which point it will be detected in plasma.
Antibody Titers • Will see Antibody Score reported with titer results. • Weak reactivity often extends beyond a 1+ which is the cut off for reporting antibody titers. • The score is calculated based on strength of reactivity of each tube. • The score can increase without the antibody titer increasing – Indicating antib0dy production or possible clinical significance • Dr. Marshall has written a letter describing the additional information being reported with antibody titers. • A copy of the letter will be available from Ronelle.
Critical Values • MVRBC staff will begin reporting and documenting who they spoke with for values that are considered critical values to MVRBC. • Each hospital is recommended to follow your own policy / procedures. • Some of the more common critical values include the following: • Positive DAT • Critical Antib0dy Titer (≥ 16, increase of 2 dilutions or a score of 10 points) • Percent compatibility of < 10% based on patient’s antibodies
Antigen Testing on Tail Segments • A new form will be faxed if you send tail segments from your inventory for antigen testing • This form (Z-132) provides verification for the hospitals that the testing was performed • Considered similar to the antigen typing tag attached to units issued to your facility
Double Red Blood Cells • Antigen typing on double red cells will now be typed individually and charged for testing performed. • Prior practice was to antigen type one unit and label both parts of the unit as antigen negative • Resulted in ONE antigen type fee • As a safety concern, the new practice will require BOTH parts to be tested and labeled as test results indicated • Resulting in an antigen testing fee for each unit ordered
Effective DATE Monday, November 7th
Final Consult Reports • Beginning Monday, November 7thfinal consult reports will not be faxed to each hospital. • The report will be placed in an envelope and sent with PMD courier to appropriate hospital • Refining process to meet our clients needs • We recognize the extra work that is involved each time a report is issued