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Design of a Sample Holder for Enhanced X-Ray Fluorescence Scanning of Brain Slices

DESCRIPTION

This project aims to develop a specialized sample holder that enhances the resolution and accuracy of the rapid scanning x-ray fluorescence technique for brain slice analysis. Key challenges include preventing sample sliding during extended periods (at least 6 hours), accommodating varying sample dimensions, ensuring samples are transport-ready, and facilitating easy loading and cleaning. The design prioritizes metal-free components, compatibility with existing stages, and adheres to a defined budget. Deliverables include a prototype, procedure documentation, a written report, and engineering drawings.

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Design of a Sample Holder for Enhanced X-Ray Fluorescence Scanning of Brain Slices

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Presentation Transcript


  1. Brain Slice Sample Holder Group 7 Jordan Moi Joshua Erikson Ho Nam Chan

  2. Client Dr. Helen Nichol • Associate Professor • Department of Anatomy and Cell Biology • University of Saskatchewan

  3. Problem • Sliding • Photons are absorbed and Scattered • Time Consuming • Potential Bio-Hazard • Not Professional

  4. Objective • To design a sample holder that will improve the resolution and accuracy of the rapid scanning x-ray fluorescence technique.

  5. Constraints • Sample must be mounted vertically for at least 6 hours without sliding. • Contain samples of varying dimensions. • Sample must be ready for scanning before it is packed for transportation. • Easy and fast to load and clean. • All components must be metal free. • Compatible with existing stages. • Budget.

  6. Project Schedule

  7. Deliverables • Prototype • Procedure • Written Report • Engineering Drawings

  8. Questions?

  9. Extras • Average brain slice mass: 150g (based on 1.0cm thickness)

  10. Pictures

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