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GUTTAE, UNGUENTA & OCULENTA

GUTTAE, UNGUENTA & OCULENTA. GUTTAE (OBAT TETES) => obat btk cair yg penggunaanya dgn cara meneteskan Indikasinya : U/obat dalam (diminum) U/obat luar (diteteskan kedlm rongga badan ). Guttae U/obat minum R/ A-D drops 15 ml S3dd gtt.v Guttae U/obat luar

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GUTTAE, UNGUENTA & OCULENTA

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  1. GUTTAE, UNGUENTA & OCULENTA

  2. GUTTAE(OBAT TETES) => obat btk cair yg penggunaanya dgn cara meneteskan Indikasinya : U/obat dalam (diminum) U/obat luar (diteteskan kedlm rongga badan ). Guttae U/obat minum • R/ A-D drops 15 ml • S3dd gtt.v Guttae U/obat luar • Guttae Auriculares = obat tetes telinga • Guttae Nasales = obat tetes hidung • Guttae Opthalmic = obat tetes mata

  3. R/Procain HCl 0,100(1%) • Antipyrin 0,500(5) • Glycerin anhyd ad 10 • S.3dd gtt.II Aur D.et.S • R/Chloramphenicol 0,500(5%) • Propylen glycol ad 10 ml • S3dd gtt. II D.et.S.

  4. Obatteteshidung • R/AntazolinHCl 50 mg (0,50%) • Naphazolinnitras 2,5 mg (0,025%) • Buffer sol. Ad 10 ml • S3dd gtt. I D.et. S. Obattetesmata • R/ BetaxolonHCl 0,56 % • Benzalkonium chloride 0,01 % • Vehikulum ad 5 ml • S2.dd.gtt.I O.D. et. S.

  5. Unguentum/zalf : sediaan ½ padatdigunakansebgobatluar Berds. Kegunaan u/terapiada 5 macam: 1.Zalf Epidermis=> melindungikulit • Vehikulum : vaselin/campuran HC 2. ZalfMukosa => melindungi/terapimukosa • Vehikulumnya : campuran vas.dgn 10-20% adepslanae 3.Zalf Endodermis => obatberpenetrasilbhdalam • Vehikulumnya : Adepslanae/lanolin 4.Cream => zalfygbanyakmengdung air • Vehikulumnya : Emulsi O/W atau W/O dptditerimasebgdasarkosmetik 5. Jelly/Gel=> Zalfygencer => sebgkontrasepsi (Spermatosida) • Vehikulumnya : Gomakasia, Carboxymetylcellulosa(CMC)

  6. Komposisi Zalf td : zat berkhasiat dan vehikulum/dasar zalf. Zat berkhasiat => tunggal/campuran sesuai dgn indikasi terapi px. Syarat Vehikulum zalf : • Indifferent • Tak merangsang kulit/mukosa • Stabil dlm penyimpanan • Tak berbau tengik • pH netral tak meninggalkan bercak pd kulit

  7. KlasifikasiVehikulumZalf 1.Gol. Hidrokarbon(HC) => hasilsampingandrdestilasiminyakbumi • Vas. Album => putih • Vas. Flavum => kuning • Paraffin liquidum => p. cair • Parrafinsolidum => p. padat/keras 2. Minyaknabati : • Ol. Sesami => m. wijen • Ol. Olivarum => m.zaitun • Ol. Arachidis => m. kacang • Ol. Cocos => m. kelapa

  8. 3 Lemak & lilinasalhewani a. Adepslanae=> lanolin anhydricum (H2O max. 0,025%) • lemakbuludomba • dapatmenyerap air max. 30%. b. Adepslanae –cum-qua => Lanolin • Campuran 75 % Adepslanaedgn 25% air • U/ buatZalf Endodermis c. Ceraflava=> lilinkuning • Dari sarangtawon/lebah => U/dasarzalf type emulsi W/O d. Cera alba => lilinputih • Dgncaramenghilangkanwarnaceraflava.

  9. R/Zinci oxyd 3 • Vaselin ad. 30 • sue • u/pruritus, psoriasis & eczem • R/Acid salacylat 0,600 • Sulfur ppt 1,200 • Vas. Flav. Ad 30 • U/ anti skabies

  10. PembuatanZalf : Ada 2 metode • Cara pencampuran & peleburan a. Pencampuran: Zatberkhasiatdicampurbersama-samadgnsegalacarasampaitercapaisediaan semi padatyghomogen (penggerusan /penguyegan) b. Peleburan: KomponendrZalfdicampurdgnmeleburbersama & didinginkansertapengadukanygkonstansampaikental ( dapatsediaansemipadatyghomogen). Sebg. PengawetZalf( takterkontaminasimikroba) • Hidroksibenzoat • Fenol-fenol • Asambenzoat • Asamsorbat

  11. Occulenta : zalf mata => Opthical ointment Zalf steril U/pengobatan mata & menggunakan dasar zalf (dz)yg sesuai Metode : Bhn obat yg steril dicampur dgn dz yg steril sedikit demi sedikit scr aseptis (alat-alat suasana steril) • R/Terramycin opht oint tube no.I • S3dd. O.D. et. S • R/ Terracortril opht oint tube no. I • suc • (signa usus cognitus) => pemakaian telah diketahui.

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