1 / 25

Eukaryotic Gene Structure and Expression: Insights into Transcription and Splicing Mechanisms

This comprehensive overview elucidates the intricate structure of eukaryotic genomes and the multifaceted processes of gene expression, encompassing transcription and post-transcriptional modifications. Key elements discussed include the classification of genes—Class I (rRNA), Class II (mRNA, snRNA), and Class III (tRNA, 5S rRNA)—along with alternative splicing and the role of the spliceosome. Additionally, the text explores gene regulation mechanisms, differential expression in gene families such as globins, and structural comparisons between prokaryotic and eukaryotic systems, with examples drawn from various model organisms.

ciaran-lang
Télécharger la présentation

Eukaryotic Gene Structure and Expression: Insights into Transcription and Splicing Mechanisms

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Eukaryotic Genome & Gene Expression

  2. Genome Structure and Postranscriptional Events Pre-mRNA Splicing PolyadenylationCapping AAAAAAA250 pppGp mRNA

  3. Eukaryotic Transcription & Translation are Compartmentalized

  4. Categories of Genes and Non-Coding Sequences Class I genes rDNA encodes rRNA Moderately repetitive sequences Transcribed by RNA polymerase I Class II genes mRNA (protein encoding) and snRNA Unique sequences Transcribed by RNA polymerase II Class III genes tRNA, 5S rRNA, U6 snRNA Moderately repetitive sequences Transcribed by RNA polymerase III Non-coding regions Repetitive elements Transposable elements (some transcribed) Pseudogenes

  5. Moderately Repetitive Sequences Code for rRNA

  6. Structure and Transcription of a Eukaryotic Gene

  7. The Globin Gene Family

  8. Differential Expression in the Globin Gene Family

  9. Processing the Ends of Eukaryotic Pre-mRNA

  10. The Spliceosome, an RNA Splicing Machine

  11. Alternative Splicing Results in Different mRNAs and Proteins

  12. Points of Regulation of Gene Expression

  13. Eukaryotic Transcription Initiation

  14. Eukaryotic Transcription Initiation

  15. Coordinating Gene Expression

  16. Protein-DNA Interactions

  17. Local Remodeling of Chromatin for Transcription

  18. A Barr Body in the Nucleus of a Female Cell

  19. A Model for X Chromosome Inactivation

  20. The Proteasome Breaks Down Proteins

  21. Comparison of Prokaryotic and Eukaryotic Genes and Genomes

  22. Comparison of E.coli and Yeast Genomes

  23. C. elegans Genes Essential to Multicellularity

  24. Arabidopsis Genes Unique to Plants

  25. Comparison of Rice and Arabidopsis Genomes

More Related