1 / 12

Introduction to Biological Databases and Data Archiving

Learn about the creation of biological databases and data archiving. Explore experimental data pipelines, stakeholder involvement, and deposition, annotation, and release policies.

coliver
Télécharger la présentation

Introduction to Biological Databases and Data Archiving

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Introduction to Biological Databases and Data Archiving Creating Archive Requirements

  2. Outline • Experimental data pipelines • Stakeholder involvement • Deposition, annotation, release policies

  3. Experimental data pipelines:Introduction

  4. Experimental Methods Used for Structure Determination First 500 1995 First 500 1991 First 500 2012 Year

  5. Information Common to all Methods • Experimenter Information • Name, ORCID id • Citation/Bibliography • Author list, journal, volume, pages, year • Biological source • Source type: natural, recombinant, or synthetic • Natural source organism, e.g. Homo sapiens • Recombinant source organism, e.g. E. coli BL21(DE3) • Polymer sequence (protein, RNA, DNA)

  6. Method-specific Information • Relevant information to archive can be divided into four broad classes • sample description • experimental setup and conditions • experimental measurements produced • interpretation of the data

  7. X-ray Crystallography Nuclear Magnetic Resonance Spectroscopy (NMR) Electron Microscopy (3DEM)

  8. Sample

  9. Experiment

  10. Measurements/Data

  11. Interpretation/Final Model

  12. This work is licensed under Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International. Funded by Grant R25 LM012286 from the National Library of Medicine of the National Institutes of Health.

More Related