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Why Implants?

Why Implants?. Above: Insertion of R etisert. What are they?. Sustained delivery to the posterior segment of the eye Can be applied to various ocular layers depending on disease: subconjuctival / intravitreal / intrasceral Implants reduce frequency of administration

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Why Implants?

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  1. Why Implants? Above: Insertion of Retisert What are they? Sustained delivery to the posterior segment of the eye Can be applied to various ocular layers depending on disease: subconjuctival/intravitreal/intrasceral Implants reduce frequency of administration compared to I.V. route, therefore they reduce risk of SEs Minimise the importance of patient compliance. • .Usually made of polymers that release a drug over a prolonged period of time. There are two types: • Biodegradable (do not need to be removed) • Non-biodegradable

  2. Side Effects and Complications Endophthalimitis Retinal Detachment Cystoid Macular Oedema Vitreous Haemorrhage

  3. Diseases of the Posterior Segment • Age-related Macular Degeneration (AMD) : Damage to retina by accumulation of drusen can cause loss of central vision. • Diabetic Retinopathy is a type of retinal damage that can lead to blindness caused by microvascular changes due to diabetes mellitus. • Glaucoma is caused by damage to the optic nerve by loss of retinal ganglion cells and increased fluid pressure in the eye. • Retinitis Pigmentosa is a progressive retinal dystrophy which affects the photoreceptors and causes loss of peripheral vision and eventually central vision.

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