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Influenza Vaccination of Health Care Personnel

Influenza Vaccination of Health Care Personnel. Sarah DuVall, M.P.H. Bureau of Immunization New York State Department of Health June, 2010. Influenza (Flu). The flu is a viral infection that can be caused by a number of different influenza strains.

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Influenza Vaccination of Health Care Personnel

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  1. Influenza Vaccination of Health Care Personnel Sarah DuVall, M.P.H. Bureau of Immunization New York State Department of Health June, 2010

  2. Influenza (Flu) • The flu is a viral infection that can be caused by a number of different influenza strains. • The flu affects the lungs, throat, nose, and other parts of the body. • Unlike the common cold, the flu comes on suddenly, can make people very sick for a week or longer, and can send them to the hospital.

  3. How Flu is Transmitted • Easily spread from person to person via respiratory droplets when an infected person coughs or sneezes. • Also spread when someone touches a surface contaminated with the virus. • Airborne transmission of the virus is possible, when an infected person is talking. • Adults shed the infectious influenza virus 1-2 days before any symptoms appear. CDC Epidemiology and Prevention of Vaccine-Preventable Diseases 2009

  4. The Flu is a Serious Illness • Flu is the 8th leading cause of death in the U.S. • Flu kills as many or more Americans than breast cancer. • Approximately 36,000 Americans will die because of the flu this year. CDC/ National Center for Health Statistics. Deaths and Mortality 2006. Poland et al., Vaccine 2005;23:2251-5.

  5. Influenza Disease Burden in the United States in an Average Year Deaths* 25,000 to 72,000 Hospitalizations* 117,000 to 816,000 Physician visits ~25 million Infections and illnesses 50 to 60 million * All-cause hospitalization and mortality associated with influenza virus infection. Thompson WW et al. JAMA. 2003;289:179-186; Thompson WW et al. JAMA. 2004;292:1333-1340; Couch RB. Ann Intern Med. 2000;133:992-998; Patriarca PA. JAMA. 1999;282:75-77; ACIP. MMWR. 2004;53(RR06):1-40.

  6. Confirmed Influenza Outbreaks in NYS Hospitals and LTCFs, by Year NYSDOH *Extended influenza season through August 2009.

  7. Morbidity from Influenza Outbreaks in NYS Hospitals and LTCFs, by Year Number Ill NYSDOH * Extended influenza season through August 2009.

  8. Impact on Health Care Facilities • Influenza is highly contagious. • Can spread rapidly through a health care facility. • Influenza is transmitted to patients by friends, family, and health care personnel (HCP). • Patients receiving home care services are at high risk of complications from influenza due to their age and medical conditions. APIC Member Initiative Protect your patients. Protect yourself. 2004

  9. Impact on Health Care Facilities • Up to ¼ of HCP contract influenza each season. • A CDC hospital survey conducted during flu season showed the following: • 35% reported staffing shortages. Poland et al., Vaccine 2005;23:2251-5.

  10. Role of HCP in Nosocomial Transmission of Influenza • Many HCP work while ill with influenza like illness (ILI). • >75% MDs and RNs surveyed reported working while ill with an ILI. • 37% of residents worked while ill with ILI. • Otherwise healthy adults may experience minimal symptoms but shed, and transmit, influenza virus. • >25% who seroconverted did not recall an ILI or any respiratory tract illness. Foy, Am J Epi, 1987 Weingarten, AJIC, 1989

  11. Essential Component of a Health Care Institution’s Occupational Health Program • Ensure the immunity of HCP to infections or diseases caused by relevant infectious agents. • Two fundamental legaland moralduties: • Protection of personnelfrom risk of the work place. • Protection of patientsfrom risks posed by infectious HCPs. Decker MD, et al. Hospital Epidemiology and Infection Control 3rd ed.

  12. Definition of HCP and Facility • Those with direct patient care: MDs, RNs, nursing assistants, therapists, technicians, emergency personnel, dental personnel, pharmacists, lab personnel, autopsy personnel, students, trainees, volunteers. • “Those not directly involved with patient care but potentially exposed to infectious agents that can be transmitted to and from HCP,” such as clerical, dietary, housekeeping, and maintenance staff. Influenza Vaccination of Health-Care Personnel Recommendations of ACIP and HICPAC-MMWR 2006

  13. Definition of HCP and Facility (con’t) • Facilities include “acute care hospitals, nursing homes, skilled nursing facilities, physician’s offices, urgent care centers, and outpatient clinics, and to persons who provide home health care and emergency medical services.” Influenza Vaccination of Health-Care Personnel Recommendations of ACIP and HICPAC-MMWR 2006

  14. All HCP Should Be Vaccinated • Regardless of their employment status. • Includes HCP with direct contact with patients (e.g., nurses, technicians, physical therapist, physicians, students). • Includes HCP without direct patient care responsibilities (e.g., environmental service worker, security, contract service workers, emergency medical personnel). Poland et al., Vaccine 2005;23:2251-5.

  15. How to Prevent Influenza Infection • Implement policies that motivate HCPs to stay home when they are sick. • Encourage appropriate infection control techniques. but this is not enough…… • HCP can still spread the flu even when they DON’T feel sick. • 50% of infected people don’t have symptoms when they are infected. • All individuals are contagious for at least 1 day before they have symptoms. • The best protection is VACCINATION. APIC Member Initiative Protect your patients. Protect yourself. 2004

  16. Why Vaccination of HCP Works • Vaccination is most effective in younger, healthier individuals. • 70%-90% effective among healthy persons <65 years of age. • Patients at highest risk, including the elderly and the immunocompromised, are least likely to develop an adequate response to the vaccine. • 30-40% effective among frail elderly persons. Therefore, vaccination of those individuals who come in contact with our vulnerable population is the most effective strategy for prevention. APIC Member Initiative Protect your patients. Protect yourself. 2004 CDC Epidemiology and Prevention of Vaccine-Preventable Diseases. 2009

  17. Benefits of Influenza Vaccination • Reduction in nosocomial influenza and influenza-related deaths. • Over 12 years in one hospital, vaccination coverage increased from 4% to 67%. • Laboratory-confirmed influenza cases among HCP decreased from 42% to 9%. • Nosocomial cases among hospitalized patients decreased 32% to 0 (p<0.0001). Salgado et al., Inf Cont Hosp Epi 2004;25:923-8 • Two randomized controlled trials evaluated impact of HCP influenza vaccination on residents in nursing homes. • They estimated >40% decrease in overall mortality among residents in the setting of high employee vaccination levels, regardless of patient vaccination levels. Carman et al., Lancet 2000;355(9198): 93—7 Potter, et al., J Infect Dis 1997;175:1--6

  18. Benefits of Influenza Vaccination • Reduction in staff illness and illness related absenteeism. • Workers who receive influenza vaccine take approximately 50% fewer sick days. • Replacement workers can result in increased expenses caused by decreased productivity, increased medical errors, and disrupted work environments. • Staff shortages can be exacerbated by influenza outbreaks. • Double shifts increase the probability of medical errors. The cost of promoting and delivering vaccinations to health care personnel is lower than the costs associated with influenza illness. Burls et al., Vaccine 2006;24:4212-21. APIC Member Initiative Protect your patients. Protect yourself. 2004

  19. Reduction in the Incidence of Influenza Infection and Related Issues in HCP Receiving Vaccination Massachusetts Medical Society, Masspro, MDPH Employee Flu Immunization Campaign Kit 2006

  20. Month of Peak Influenza Activity United States, 1976-2006 45% There is usually ample time to vaccinate HCP before influenza occurs! 19% 13% 13% 3% 3% MMWR 2007;55(RR-6):5

  21. Vaccination Rates Need Improvement • In 2006-07, only 44% of HCP were immunized against influenza in the U.S. • Includes all HCP who have contact with patients. • Despite aggressive national efforts, rates of HCP immunized have stayed around 40%. MMWR.2009:58(early release): 1-52

  22. Barriers to Vaccination • Reasons HCP decline influenza vaccination: • Misconception that vaccination can cause influenza (10-45%). • Fear of adverse events (8-54%). • Times/locations of vaccination were unsuitable (6-59%). • Perception that they are not at risk (6-58%). • Fear of injections (4-26%). • Lack of vaccine efficacy (3-32%) - except physicians. • Doubt that influenza is a serious disease (2-32%). • Two main barriers: • Misperception of influenza, its risks, the role of HCP in its’ transmission to patients, and the importance and risks of vaccination. • Lack of (or perceived lack of) conveniently available vaccine. • Hofman et al., Infection 2005;34:142-147

  23. Reasons for Rejecting Vaccination Among Health Care Personnel Barriers to Vaccination Primary Reasons >30% *Vaccine needs to be made available during all employment shifts. Christini AB, et al. Infect Control Hosp Epidemiol 2007;28:171-7

  24. Reasons for Accepting Vaccination Among Health Care Personnel Motivators for Vaccination Primary Reasons >60% Christini AB, et al. Infect Control Hosp Epidemiol 2007;28:171-7

  25. Joint Commission Quality MeasureHCP Influenza Vaccination Levels Standards for Influenza Vaccination Programs in Accredited Institutions, 2007 • Annual influenza vaccination program that includes at least staff and licensed independent practitioners. • Provide access to influenza vaccination on-site. • Educate staff and licensed independent practitioners about influenza vaccination; non-vaccine control measures; and diagnosis, transmission and potential impact of influenza. • Annually evaluate vaccination rates and reasons for nonparticipation by staff and licensed independent practitioners. • Implement enhancements to the program to increase participation. This standard is an accreditation requirement as of January 1, 2007.

  26. Improving Compliance • Leadership Support • Education • Accessibility • Incentives • Feedback and Follow-up • Mandatory Vaccination • Measure Vaccination Rates

  27. Leadership Support • Leadership involvement is essential for a successful program. • Leadership is responsible for: • Establishing expectation that influenza vaccination of HCP is a patient safety issue. • Making sure vaccination program has adequate resources. • Reducing or eliminating barriers. • Being a role model. CDC and The Joint Commission Improving Your Vaccination Program 2009

  28. Education • HCP need to know when and where education and vaccinations will be offered and the importance of the vaccination. • Promoting vaccinations can take many forms in many venues, including: • E-mail notice and reminders. • Newsletters, with regular updates. • Posters.* • Screen savers. • Stickers worn by health care personnel.* • Messages delivered in person at meetings or health fairs.* *NYSDOH and the CDC offer FREE materials, www.nyhealth.gov/www.cdc.gov CDC and The Joint Commission Improving Your Vaccination Program 2009

  29. Accessibility • Provide free vaccines at work. • Use leaders as supportive role models. • Use vaccination clinics, mobile carts. • Link vaccinations to required activity. • Mandatory tuberculin skin testing. • Annual safety competency or skills days. • Disaster drills. CDC and The Joint Commission Improving Your Vaccination Program 2009

  30. Incentives for HCPs • Financial incentives (discounts on benefits, impact on merit increases, consideration in granting decisions regarding time off). • HCP recognition. • Need to understand HCPs motivation. CDC and The Joint Commission Improving Your Vaccination Program 2009

  31. Feedback and Follow-up • Review list of non-vaccinated employees weekly. • Provide weekly reminders to supervisors with list of non-vaccinated employees. • Identify central authority figure to add pressure to comply. Buy-in from administration is key. • Put pressure on employee to make active decision, instead of allowing passive avoidance. • Continue until goals are met. McCullers JA, et al., Inf Cont Hosp Epi, 2006;27:77-9.

  32. Mandatory Vaccination Multiple groups support mandatory vaccination: • New York State Department of Health • American College of Physicians “An ethical obligation” • Association for Professionals in Infection Control and Epidemiology “HCP have an obligation…” • Infectious Disease Society of America “…likely to be the most effective means to protect patients against the transmission of seasonal and H1N1 influenza by HCWs.” • National Patient Safety Foundation • U.S. Department of Defense (DOD) • Mandatory seasonal influenza vaccination requirement for civilian health care personnel who provide direct patient care in DOD facilities.

  33. Battle Creek Health System, Battle Creek, MI Barnes Jewish Corporation (BJC) HealthCare, St. Louis, MO Bronson Methodist Hospital, Kalamazoo, MI Capital Region Medical Center, Jefferson City, MO Children's Hospital of Orange County, CA Children’s Hospital of Philadelphia Children's Hospital of The King's Daughters Health System, Norfolk, VA Creighton University Genesis HealthCare System, Zanesville, OH Fort Walton Beach Medical Center, Fort Walton Beach, FL Hoag Hospital, Newport Beach, CA Hospital of the University of Pennsylvania Johns Hopkins Health System, MD Kewanee Hospital, Kewanee, IL Lakeview Medical Center, Rice Lake, WI Long Beach Memorial Medical Center, Long Beach, CA Loyola University Health System, Chicago, IL MedStar Health, Maryland and Washington, DC Michigan State University/Kalamazoo Center for Medical Studies Miller Children's Hospital, Long Beach, CA New York-Presbyterian Hospital, New York Orange Coast Memorial Medical Center, Fountain Valley, CA Pacific Hospital of Long Beach, CA Petaluma Valley Hospital, Petaluma, CA Saddleback Memorial Medical Center, Laguna Hills, CA Saint Alphonsus Regional Medical Center, Boise, Idaho Santa Rosa Memorial Hospital, Santa Rosa, CA Spectrum Health Hospitals, Grand Rapids, MI St. Joseph Health System, Orange, CA St. Jude Medical Center, Fullerton, CA Swedish Medical Center, Englewood, CO Tri-Health, Good Samaritan and Bethesda North Hospitals, Cincinnati, OH UC ((University of California) Davis Health System, Sacramento, CA UC (University of California) Irvine Healthcare, Orange, CA Virginia Mason Medical Center, Seattle, WA U.S. Health Systems with HCP Influenza Vaccination Mandates (4/10*) *http://www.immunize.org/laws/influenzahcw.asp

  34. Influenza Vaccination Coverage by Employer Vaccination Policy, 2009 MMWR Vol. 59 / No. 12 April 2, 2010

  35. Measure HCP Vaccination Rates • Measurement is essential to your program. • Only through measurement is it possible to determine if performance is getting better, worse, or staying the same. • Capture alternative administration (for example: clinics, physician offices, pharmacies, etc.). CDC and The Joint Commission Improving Your Vaccination Program 2009

  36. Purchasing Influenza Vaccine • Pre-book vaccine in January or February. • Influenza vaccines take months to produce. • Vaccine manufacturers are hesitant to risk producing products they will be unable to sell. • For more information on distributors and influenza vaccine availability, please visit the following websites: • Influenza Vaccine Distributor Information http://www.flusupplynews.com/resources.cfm • Influenza Vaccine Availability Tracking System (IVATS) http://www.preventinfluenza.org/ivats/ivats_healthcare.asp

  37. Purchasing Influenza Vaccine Available Vaccines • 4 trivalent inactivated vaccines (TIV), administered intramuscularly: • Fluzone® - 6 mos and older • FLUVIRIN® - 4 yrs and older • FLUARIX™ - 18 yrs and older • FluLaval™ - 18 yrs and older • 1 trivalent live, attenuated vaccine (LAIV) administered as a nasal spray: • FluMist® - healthy people 2 to 50 years old

  38. Vaccine Information Using Nasal Spray (LAIV ) • LAIV may be used for healthy, non-pregnant HCP <50 yrs old. • At times of vaccine shortage, LAIV is “especially encouraged” unless contraindicated. • HCP who work with severely immunocompromised patients in a protected environment should NOT receive LAIV (bone marrow transplant unit staff). • LAIV can be used to vaccinate HCP who have close contact with persons with a lesser degree of immunosuppression(e.g., persons with diabetes, persons with asthma taking corticosteroids, or persons infected with HIV). Transmission of LAIV has NEVER been documented in a health care facility. CDC and The Joint Commission Improving Your Vaccination Program 2009

  39. Vaccine Information Efficacy • Intramuscular Injection (TIV): Effectiveness in adults < 65 years • 80% (95% CI 56% to 91%) when vaccine matched circulating strain. • 50% (95% CI 27% to 65%) when not well matched. Jefferson, et al. Cochrane Database Syst Rev. 2007 Apr 18;(2):CD001269. • Nasal Spray (LAIV): Effectiveness in healthy adults • Overall efficacy of LAIV and inactivated influenza vaccine in preventing; laboratory-documented influenza, 85% LAIV and 71% TIV. Treanor et al., Vaccine 1999;18:899—906. • Even with suboptimal vaccine-wild virus match: • 24% fewer febrile upper respiratory illness episodes (URI). • 27% fewer lost work days due to febrile URI. • 41%-45% fewer days of antibiotic use. Nichol et al., JAMA 1999;282:137—44.

  40. Vaccine Information Adverse Events • Intramuscular Injection (TIV) • Local Reactions - 15%-20% (TIV) • Fever, malaise - not common • Allergic reactions - rare (<1 in 1 million, Anaphylaxis) • Neurological - rare (1 in 1 million, Guillain-Barre Syndrome) • U.S. Department of Health & Human Services Influenza Vaccination of Health-care Personnel 2008 • Nasal Spray (LAIV) • Local Reactions: • cough 14% • runny nose 45% • sore throat 28% • chills 9% Belshe RB et al. Clin Infect Dis 2004;39:920--7.

  41. Neither LAIV or TIV Vaccines Can Cause Influenza Disease • TIV contains only non-infectious fragments of influenza virus. • LAIV cannot replicate in the lower respiratory track.

  42. Influenza Vaccination Mandate • SHRPC adopted an emergency regulation, 10 NYCRR, Subpart 66-3. • Applied to HCP in certain Health Care Facilities. • Direct patient contact • Contact with those who have direct patient contact. • ONLY medical exemptions allowed. • Began- August 13, 2009, effective immediately; • Suspended-October 23, 2009 • Expired (no-renewal)-November 11, 2009. • Vaccination or provision of documentation no later than November 30 of each year • New Employees- to be vaccinated November- April. • NYSDOH is currently pursuing a permanenet regulation.

  43. Hospital Survey • New York State (including New York City) • 211 Hospitals--------100% compliance

  44. % of Health Care Personnel (HCP) Vaccinated in New York State • 66% increase in the # of HCP Vaccinated with the mandate in place. • 62% less HCP were vaccinated against H1N1 influenza than seasonal influenza.

  45. The % vaccinated is the same for Seasonal influenza and lower for H1N1 influenza.

  46. Reasons for Outliers • High Medical Exemption Rates • “Local physicians opposed the mandate” • Problematic medical exemptions require follow up. • Low Vaccination Rates • HCP strongly opposed the mandate. • HCP concerned about vaccine safety. • Limited Vaccine Supply.

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