1 / 25

ANATOMY AND TIME Barry Smith

ANATOMY AND TIME Barry Smith. SNAP AND SPAN. To understand relations between universals. Reference to times and instances are important A derives from B concept A derives from concept B. Official OBO definition. term: derived_from definition: Any kind of temporal relationship,

dane-hodges
Télécharger la présentation

ANATOMY AND TIME Barry Smith

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. ANATOMY AND TIMEBarry Smith

  2. SNAP AND SPAN

  3. To understand relations between universals • Reference to times and instances are important • A derives from B • concept A derives from concept B

  4. Official OBO definition • term: derived_from • definition: Any kind of temporal relationship, • such as derived_from, translated_from

  5. Better Definition • A derives from B • for any instance x of A there is some instance y of B such that x exists earlier than y and

  6. What is an anatomy standardization for? • Anatomy: • across species (human, mouse) (SAEL) • across time (development, growth, aging) • from generic (normal + abnormal) • to instance-based) • Tied to: genomic • clinical (disease pathways)

  7. FMA = (AT, ASA, ATA, Mk) • AT = Anatomy Taxonomy • ASA = Anatomical Structural Abstraction • Mk = Metaknowledge

  8. FMA = (AT, ASA, ATA, Mk) • ATA, or Anatomical Transformation Abstraction describes the time-dependent morphological transformations of the concepts represented in the taxonomy during the human life cycle, which includes prenatal development, postnatal growth and aging;

  9. FMA = (AT, ASA, ATA, Mk) • ATA, or Anatomical Transformation Abstraction describes the time-dependent morphological transformations of the concepts represented in the taxonomy during the human life cycle, which includes prenatal development, postnatal growth and aging;

  10. single-cell zygote • multi-cell zygote • morula • early blastocyst • gastrula • new born • infant • adolescent • young adult

  11. A sequence of SNAP ontologies

  12. development processes aging processes growth processes physiological processes together with SPAN ontologies for processes/transformations SNAP

  13. each of these at a plurality of levels of granularity cellular subcellular molecular physiological processes SNAP

  14. time SNAP

  15. canonical vs. instantiated time

  16. undeformed  deformed time

  17. these are not instances undeformed  deformed time

  18. WINDOWS ON REALITY undeformed  deformed time

  19. SYMBIOSIS OF KNOWLEDGE ABOUT UNIVERSALS AND INSTANCES undeformed  deformed time

  20. undeformed  deformed time

  21. undeformed  deformed human chimpanzee mouse fly yeast bacteria time

  22. undeformed  deformed human chimpanzee mouse fly yeast bacteria time

  23. A Proposed Standardization • relations

  24. A Proposed Standardization • OBO Relations Ontology

  25. A Proposed Standardization • OBO Relations Ontology • is part of • is member of (a collection) • is location of -- is contained in … • is connected to • is later than – is simultaneous with … • is bearer of • is function of • causes • is functioning of

More Related