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Whole Brain Fractional Anisotropy (FA) and Apparent Diffusion Coefficient (ADC) Histogram Analysis

Whole Brain Fractional Anisotropy (FA) and Apparent Diffusion Coefficient (ADC) Histogram Analysis Xavier Golay PhD., Srirama V. Swaminathan PhD., Truman R. Brown PhD., Gary M. Brittenham MD., Christina Tosti MS. March 13, 2006. Histogram Procedure

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Whole Brain Fractional Anisotropy (FA) and Apparent Diffusion Coefficient (ADC) Histogram Analysis

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  1. Whole Brain Fractional Anisotropy (FA) and Apparent Diffusion Coefficient (ADC) Histogram Analysis Xavier Golay PhD., Srirama V. Swaminathan PhD., Truman R. Brown PhD., Gary M. Brittenham MD., Christina Tosti MS. March 13, 2006

  2. Histogram Procedure • PAR/REC diffusion data is used to create FA, ADC, and color maps (DTIStudio, JHU). • A brain extraction tool is used to create a mask based on the original diffusion data (FSL_BET). • Mask from the diffusion data is applied to the FA and ADC map (FSL_avwmaths). • Image histogram of the whole stripped brain is calculated and normalized (ImageJ, Excel).

  3. Subtraction of FA maps (avwmaths, FSL) for pt07 exam one and exam two. Attempt was to show grey-white matter contrast. Image was coregistered (FLIRT, FSL) and smoothed by ImageJ.

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