Nanotechnology CancerResearch Kenneth Milne Introduction to Nanotechnology 2 December 2013
Progression in Cancer Treatment • Better Sunscreen, nanoparticles are more effective in absorbing light, especially UV light • Titanium dioxide or zinc oxide nanoparticles • Don’t break down in the sun • Stronger protection, less exposure. • Few health concerns(.01% if zinc entered blood stream) • Applications to other fields: biology, chemistry, physics and egineering.
Nanoparticles used to detect and monitor cancer cells using nano sized imaging agents. • Conjugated with biomolecular targeting ligands used to detect tumors. -Gold nanoparticles
Targeted Drug Delivery • Loaded with drugs and targeted at cancer cells • Able to pass through the body • Infrared light, Heat up cancer cells
Future Plans -Engineer a nanoparticle that will actively interact with the immune system. • -Better nanotechnologies to detect cancer and destroy it. Stop cancer before it develops. Gain approval for diagnostic tests -understand patient interactions to targeted therapies. -identify ligands that can target both tumor cells and the tumor microenvironment simultaneously Diagnose and identify cancerous cells earlier. -Use on humans and destroy tumor and cancer cells.
Works Cited • Evironmental Working Group, “Nanoparticles in suncreen,” Enironmental Working Group website, March 2013, web, November 26, 2013 • Acosta, Richard, “Nanotechnology in Cancer Treatment and Detection,” Paul Hansma Research Group, Hansmalab website, 18 August 2010, web/pdf, 20 November 2013 • Mansoor, Ali, Mohazzabi, Pirooz, McCormick, Percival, Siavash, Jabari, “ Nanotechnolog in Cancer Prevention, Detection and Treatment: Bright Future Lies Ahead,” Inderscience Enterprises Ltd. World Review of Science, Technology and Sustainable Development, November 2007, Web, 18 November 2013 • Grossman, J. H., & McNeil, S. E. (2012). “NANOTECHNOLOGY IN CANCER MEDICINE”. Physics Today, 65(8), 38-42. August 2012, Web, 26 November 2013 • Jones, Dan, “Cancer Technology, Small but Heading For the Big Time,” Nature Publishing Group, Nature Website, March 2007, Web, 20 November 2013 • Landau, Elizabeth, “Nanotech Cancer Treatment Shown to Work in Humans,” CNN, CNN website, 22 March 2010, 16 November 2013 • Misra, R., Acharya, S., & Sahoo, S. K. (2010). “Cancer nanotechnology: application of nanotechnology in cancer therapy.” Drug Discovery Today, 15(19/20), 842-850. doi:10.1016/j.drudis.2010.08.006, 24 November 2013. • Nanotechnology Now, “Current Nanotechnology Applications,” 7th Wave, Inc., Nanotechnology Now, 22 May 2012, Web, 18 November 2013 https://www.google.com/search?q=nanotechnology+imaging+agents&source=lnms&tbm=isch&sa=X&ei=eRmcUtHjEIG9yAHdfQ&ved=0CAcQ_AUoAQ&biw=1344&bih=632 • https://www.google.com/search?q=nanotechnology+imaging+agents&source=lnms&tbm=isch&sa=X&ei=eRmcUtHjEIG9yAHdfQ&ved=0CAcQ_AUoAQ&biw=1344&bih=632 • http://nano.cancer.gov/objects/pdfs/CaNanoPlan.pdf • http://www.dnatube.com/video/7497/Nanotechnology-and-the-future-of-cancer-treatment