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p110

EGFR-PI3K-mTOR signaling in glioma. EGFR. p. p. PIP 3. PIP 2. p. p. p. p85. p110. PDK 1. PI3K. PLC . PTEN. PKC. Ser473. Thr308. MAPK. p. p. Akt. p. TSC1/TSC2. mTOR. Raptor. Rictor. mTOR. mTORC1. mTORC2. mTOR. p. p. 4E-BP. S6K. Autophagy. Cell growth, Cell death.

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p110

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  1. EGFR-PI3K-mTOR signaling in glioma EGFR p p PIP3 PIP2 p p p p85 p110 PDK 1 PI3K PLC PTEN PKC Ser473 Thr308 MAPK p p Akt p TSC1/TSC2 mTOR Raptor Rictor mTOR mTORC1 mTORC2 mTOR p p 4E-BP S6K Autophagy Cell growth, Cell death

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