Lipid Stabilization of AqpZ Channel Modulation

Mar 01, 2025

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Cardiolipin uniquely stabilizes the AqpZ channel, affecting its function. Research by Laganowsky et al. in Nature (2014) highlights the impact of lipids on channel stability and modulation.

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Lipid Stabilization of AqpZ Channel Modulation

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AqpZ is indiscriminately stabilized by lipids with the exception of cardiolipin, a lipid that stabilizes the channel significantly and modulates its function. ALaganowskyet al. Nature 510, 172-175 (2014) doi:10.1038/nature13419

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