Effects of ITF2357 on Cell Viability and Protein Expression in LCSC136

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This study investigates the impact of ITF2357 treatment (0.1 to 5 μM) over 72 hours on cell viability and key protein levels, including cleaved PARP and HSP70/72, in LCSC136 cells. We assessed the viability percentage and observed alterations in the expression of acetylated histone H3, linking the compound's effects to potential mechanisms of action. Results suggest promising therapeutic implications for ITF2357 in cancer treatment by modulating cell survival pathways.

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Feb 15, 2026

itf2357 lcsc136 cells cell viability apoptosis markers hsp7072 parp cleavage acetylated histone cancer therapy

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Effects of ITF2357 on Cell Viability and Protein Expression in LCSC136

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Figure S5 B A ITF2357 (μM, 72h) 1 2.5 5 - 0.1 0.5 Ac-H3 Viability (%) PARP Cleavedform HSP70/72 LCSC136 ITF2357 (μM)

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