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Learn about tetrahydrocannabinol (THC), a psychoactive compound found in cannabis, its effects on the body, medicinal uses, and potential risks. Explore how THC interacts with the endocannabinoid system and its impact on cognitive functions. Discover reliable sources for more information.
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THC: tetrahydrocannabinol MALI BOWERS PHYSIOLOGY FALL 17 THC PRESENTATION
WHAT IS THC? • psychoactiveorganic compound • (sī’kōˈak’tiv / adj./ affects the CNS) • Molecular formula: C21H30O2 (delta-9-THC) • Molecular weight: 314.4 g/mol
A.K.A • Weed • Pot • Cannabis • Ganga • Grass • Reefer • Blaze • Skunk • Join • Green • Mary-jane • Herb • Chronic M A R I J U A N A
HOW IT WORKS Inhibitoryneurotransmitter made by your body, anandamide • Mimics NT anandamide (produced by body) • Binds to cannabinoid receptors,affects CNS + PNS • Inhibitory effects (hyperpolarizes postsynaptic cells, IPSP) Synthetic or phytocannabinoid THC Cannabinoid Receptor
CANNABINOID SYNAPSE NORMAL SYNAPSE
MEDICINALORMISUSED ????????? • TCH exposure has developmental consequences: affects cognitive abilities/IQ if used regularly in teens • Children exposed to marijuana in the womb have an increased risk of problems with attention, memory, and problem-solving • Not “addictive” (induces withdrawal symptoms) but people can become dependant • Augment schizophrenic tendencies
SOURCES • https://www.vice.com/en_us/article/bnp4bv/how-and-why-your-brian-makes-its-own-cannabinoids • http://headsup.scholastic.com/students/the-science-of-marijuana • https://www.livescience.com/24553-what-is-thc.html • https://www.drugabuse.gov/publications/drugfacts/marijuana • http://www.emcdda.europa.eu/publications/drug-profiles/cannabis • https://www.southcountymeds.com/how-thc-works-in-the-body/ • https://www.drugabuse.gov/related-topics/adolescent-brain/longitudinal-study-adolescent-brain-cognitive-development-abcd-study • http://thelancet.com/journals/lancet/article/PIIS0140-6736(10)60935-X/fulltext • http://reset.me/story/anandamide-putting-the-bliss-molecule-to-work-for-your-brain/ • http://headsup.scholastic.com/students/the-science-of-marijuana • http://headsup.scholastic.com/students/endocannabinoid