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The study by Tumbale et al. in Nature (2013) details how human APTX recognizes adenylated RNA-DNA junctions, shedding light on DNA repair mechanisms. This crucial finding enhances our understanding of DNA damage responses and potential therapeutic targets.
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Recognition of adenylated RNA–DNA junctions by human APTX. P Tumbaleet al. Nature 000, 1-5 (2013) doi:10.1038/nature12824