VIROLOGY Claude MUVUNYI M.D, Ph.D. Head of Microbiology Unit/NRL RBC
VIROLOGY • Module:INFECTION II • Definition: Study of viral structure and behavior, HOW disease occurs and WHY? • Course Intent: Undergraduate students (Medicine and Pharmacy). All aspects of virology will be covered including • Viruses Structure, • replication and expression mechanisms, • Pathogenesis and epidemiology • host defenses • Methods for diagnosis
VIROLOGY • Prerequisites: • Cell and Molecular Biology: This is an absolute requirement!! If you don’t have a solid understanding of cell structure and the processes of transcription and translation, drop the class now. • Microbiology:Also listed as a requirement, but I’ll let it slide if you’ve had #3. • Genetics:recommended, but not required • Organic chemistry and biochemistry are very helpful, but not required • Immunology is also helpful, but not required
VIROLOGY • Required text: • E.K. Wagner and M.J. Hewlett, "Basic Virology", 2nd Ed. Blackwell Science, 2004. • Virology: Principles and Applications. 2007. Authors: Carter and Saunders (Wiley Publishing) • Recommended reference texts: • S.J. Flint et al., "Principles of Virology: Molecular Biology, Pathogenesis, and Control", ASM Press, 2000. • Internet resources: Animations and other materials can be found at http://www.blackwellpublishing.com/Wagner/default.asp. • Class notes: You will have access to all lecture material Syllabus • Power points slides • syllabus as hard and soft files.
VIROLOGY • Requirement to sit for Exams: 85 % class attendance • Grade Determination: The grade in this class is determined by the following: • Lecture Exam (multiple choice or short answers) – 70% • Presentation or Assay (TP): 30%
VIROLOGY • Course Outcomes: At the end of the course, students should be able to: • Diagram replication strategies for the major classes of viruses • Explain different strategies for viral gene expression, infection patterns and pathogenesis • Explain the differences between different classes of viruses • Identify reliable sources of information about epidemics, emerging viruses, and vaccination programs • Describe prevention and treatment strategies associated with various viral infections
VIROLOGY • SEQUENCE OF LECTURE MATERIAL • SECTION 1: Viral definition, structures and classification • SECTION 2: Replication of the virus • SECTION 3: Viral Pathogenesis • SECTION 4: Viral diseases and Epidemiology • SECTION 5: Means of viral infection diagnosis
VIROLOGY You’re from Kigali? Wow! Say… You have lovely eyes Hey, everyone! We’re going to Butare