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Platelet Reactivity Meta-Analysis: Predicting MACE After PCI

This meta-analysis evaluates the clinical significance of platelet reactivity measured by VerifyNow P2Y12 in clopidogrel treatment for PCI patients. The study, based on 6 datasets, shows that on-treatment platelet reactivity predicts major adverse cardiac events.

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Platelet Reactivity Meta-Analysis: Predicting MACE After PCI

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  1. PlateletReactivity – Meta-Analysis Objective: to evaluate the clinicalsignificance of plateletreactivitymeasured by VerifyNowP2Y12 assay of clopidogreltreatmentStudy: individualpatient-level data obtainedfromdatabankusing 6 studiesPopulation: patients undergoing PCI and usingclopidogrelEndpoint: composite of death, MI or stentthrombosis

  2. PlateletReactivity – Meta-Analysis

  3. PlateletReactivity – Meta-Analysis

  4. PlateletReactivity – Meta-Analysis Conclusion the level of on-treatmentplateletreactivitymeasuredwith P2Y12assaypredicts MACE after PCI Brar JACC 2011;58:1945-54

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