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Case Presentation

Case Presentation. Discussion of Question 1. Discussion of Question 2. Case Presentation (cont). Discussion of Question 3. Focus on Nausea: Current Trends in Patient Assessment and Treatment Approaches. Proposed Pathways of Chemotherapy-Induced Emesis. Emetic Risk Categories.

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Case Presentation

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Presentation Transcript

  1. Case Presentation

  2. Discussion of Question 1

  3. Discussion of Question 2

  4. Case Presentation (cont)

  5. Discussion of Question 3

  6. Focus on Nausea: Current Trends in Patient Assessment and Treatment Approaches

  7. Proposed Pathways of Chemotherapy-Induced Emesis

  8. Emetic Risk Categories

  9. Risk Factors for Chemotherapy-Induced Nausea and Vomiting

  10. Classification of Chemotherapy-Induced Nausea and Vomiting

  11. Delayed Emesis

  12. Treatment Algorithm: Control of Chemotherapy-Induced Emesis

  13. Serotonin Antagonists and Dosage

  14. Off-Label Agents for the Control of Chemotherapy-Induced Nausea

  15. Gabapentin for the Control of CINV: Study Design

  16. Gabapentin: Control of CINV

  17. Olanzapine + Palonosetron + Dexamethasone vs Aprepitant + Palonosetron + Dexamethasone: Study Design

  18. Olanzapine as an Antiemetic

  19. Case Presentation (cont)

  20. Discussion of Question 4

  21. Case Presentation (cont)

  22. Discussion of Question 5

  23. Discussion of Question 6

  24. Discussion of Question 7

  25. Discussion of Question 8

  26. CINV: Links to Anorexia/Cachexia

  27. Questions to Consider

  28. Emetic Reflex Arc and Anorexia: Similar Pathways

  29. Anorexia Seems to Improve With Effective Chemotherapy

  30. “Adjuvant chemotherapy is linked to weight gain….”

  31. Caloric Intake is Not Necessarily Reduced/Increased With Adjuvant Chemotherapy vs Localized Treatment

  32. Point #1: Main Concepts

  33. Questions to Consider

  34. Multiple, placebo-controlled clinical trials suggest the following:

  35. Palliating Anorexia in Cancer Patients

  36. Megestrol Acetate Appears to Also Help With Vomiting (This Shouldn’t Be Surprising)

  37. Point #2: Main Concepts

  38. Recognizing the Importance of Cachexia in Cancer

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