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Central Dogma and Gene Regulation

Central Dogma and Gene Regulation. Bill Staddon Eastern Kentucky University. “A man learns to skate by staggering about and making a fool of himself. Indeed he progresses in all things by resolutely making a fool of himself.” George Bernard Shaw . Context. Microbiology for majors

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Central Dogma and Gene Regulation

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  1. Central Dogma and Gene Regulation Bill Staddon Eastern Kentucky University “A man learns to skate by staggering about and making a fool of himself. Indeed he progresses in all things by resolutely making a fool of himself.” George Bernard Shaw

  2. Context • Microbiology for majors • 300 level • I teach lecture and lab

  3. Holy Grail! Midterm and Final Questions 1. Application/Synthesis Problems 2. Work through in steps using Immediate Feedback Assessment Technique form

  4. Learning Outcomes – Central Dogma and Gene Regulation • Students will describe how information flows in a bacterial cells using appropriate vocabulary. • Students will describe how gene expression is controlled in inducible and repressible systems. • Students will explain why regulation of gene expression is necessary. • Students will solve problems involving replication, transcription, translation and gene expressions by applying and synthesizing key concepts. • Course Learning Outcome • Students will compose and communicate answers to problems

  5. Central Dogma Sequence Central Dogma check. Students, working in groups, will demonstrate replication, transcription and translation. Students will draw cards to determine which process they model. Central Dogma vocabulary check. Students will draw cards to answer selected questions. Students will watch video on replication and practice steps using manipulatives. Students will watch videos on transcription and translation then practice steps using manipulatives. Blackboard Quizzes on Replication Blackboard Quizzes on transcription and translation • Block questions • Checks • Quizzes in class • Blackboard quizzes

  6. Gene Expression Sequence Students will compare and correct strip sequences, diagrams and odds and sods. Then they will make diagrams and correct with the help of their peers. Followed by block questions. Individual/ Group Quiz on operons. Group quiz will have additional application/synthesis. Students will describe why they made errors. Students will watch videos about the lac and trp operons. They will prepare strip sequences. Students will complete Blackboard quizzes on operons. • Block questions • Checks • Quizzes in class • Blackboard quizzes

  7. Problems for Oral Presentation Students will work in varied groups to solve a problem about gene expression. Students will work in varied groups to solve a problem about the central dogma. Students will prepare answers/mini presentations Students will give oral presentations in my office.

  8. The Last Bits Students will work through problems step by step on the final exam. Students will practice working through problems step by step on Blackboard. Students review content on Blackboard.

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