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Hydroxypropylation of starch enhances its potential applications, especially its use in specialized drug delivery systems. The study aimed at exploring the sustained release property of hydroxypropylated (HP) cassava and potato starches in diclofenac sodium tablet formulations. Native cassava and potato starches were hydroxypropylated and used in the preparation of batches of diclofenac powder blends and granules either as powders (filler) or mucilage (binder). Powder blends/granules flow properties were investigated as well as drug-excipient interaction using Fourier transform infra-red
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