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Exam 3 (mean 76%)

Exam 3 (mean 76%). Today-Ch 13 Announcements Look for Chapter 12 and 13 quizzes posted this weekend. Exam 4 covers Chapters 12, 13 and 16 (last exam you can drop. Everyone must take the final exam). Biology 190 Chapter 16 pictures. DNA Replication occurs at the “S” stage of mitosis.

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Exam 3 (mean 76%)

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  1. Exam 3 (mean 76%)

  2. Today-Ch 13 • Announcements • Look for Chapter 12 and 13 quizzes posted this weekend. • Exam 4 covers Chapters 12, 13 and 16 (last exam you can drop. Everyone must take the final exam)

  3. Biology 190Chapter 16 pictures

  4. DNA Replication occurs at the “S” stage of mitosis

  5. Fig 5.26 Nucleotides U

  6. Fig 16.5 One DNA strand. A C C C C A G

  7. Fig 16.6 Double Helix A C C C C A G -T -G -G -G -G -T -C

  8. Chargaff’s Rule

  9. Question 16.1

  10. Functions of Proteins • Structural • Catalytic activity • Immunity • Regulation • Poisons • Transport molecules • Hormones • Fluid and electrolyte balance • Sources of energy

  11. Fredrick Griffith’s Experiments Polysaccharide Coat

  12. Fredrick Griffith’s Results Live R-strain picked up DNA from the S-strain. Contains genes for “smooth coat”.

  13. Alfred Hershey and Martha Chase

  14. How viruses (phages) infect bacteria

  15. Fig 16.4 Hershey and Chase

  16. Watson and Crick

  17. Rosalind Franklin’s Data(Maurice Wilkins’ Lab)

  18. What exactly ISthe structure of DNA?

  19. Chargaff’s Rule

  20. Nucleotide base pairing

  21. Fig 16.7 Structure of DNA

  22. Nobel Prize- 1962 Wilkins Crick Watson

  23. Figure 16.9 Semiconservative Model for DNA Replication Parental strands (template strands) Daughter strands

  24. DNA Origin of Replication Bacteria have one origin of replication. Fig 16.12 Eukaryotic organisms have multiple origins of replication.

  25. Unwinding DNA Single-stranded Binding Proteins

  26. Nucleoside Triphosphate

  27. Fig 16.13 DNA Polymerase (Old strand) (Parent strand) (Daughter strand) P

  28. Questions 6.3 & 6.4

  29. Fig 16.14 Leading Strand 3’ 5’ Old strands Parent strands Template strands Replication Fork 5’ 3’ 5’ 3’ 3’ Lagging Strand 5’ 3’ 5’ 3’ 5’ 5’ 3’ 3’ 5’

  30. Fig 16.14 DNA Polymerase III DNA Ligase

  31. Fig 16.13 DNA polymerase needs a 3’ -OH group

  32. Fig 16.16

  33. Fig 16.16. Review of Bacterial DNA Replication SS binding proteins Helicase

  34. Fig 16.18DNA shortening and telomeres

  35. Mismatch repair 2 Purines = bulge G A 2 Pyrimidines = dimple T C

  36. Fig 16.17 Excision Repair

  37. Xeroderma Pigmentosa

  38. In very, very, vary rare cases mutations have a selective advantage

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