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Effective Treatments for Elderly Patients with Multiple Myeloma and CLL

This document addresses critical questions regarding treatment options for elderly patients with multiple myeloma (MM) and chronic lymphocytic leukemia (CLL). It highlights the treatments to avoid in MM patients planning autologous peripheral blood stem cell transplants and identifies the most effective and best-tolerated approved treatments for newly diagnosed CLL in the elderly, based on current clinical trial data. Understanding these options is essential for optimizing patient care and improving outcomes in this vulnerable population.

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Effective Treatments for Elderly Patients with Multiple Myeloma and CLL

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  1. ARS Question #1 • Which treatment for MM should be avoided in patients wishing to pursue autologous peripheral blood stem cell transplant but is often used in elderly? A. Bortezomib B. Lenalidomide C. Melphalan D. Prednisone

  2. ARS Question #2 • According to the most current clinical trial data, which of the approved treatments for elderly patients with newly diagnosed CLL is most effective and best tolerated? A. Chlorambucil B. Fludarabine C. Rituximab D. Ofatumumab E. Lenalidomide

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