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Comprehensive Analysis of Bcl-2 Family Gene Patterns: Mer Size Distribution and Functionality

This study presents a detailed analysis of the Bcl-2 family of genes, focusing on the distribution of molecular patterns, particularly the prevalence and functionality of 7-mer, 9-mer, 12-mer, and 13-mer sequences. Critical insights are provided into the roles of various members such as Bcl2l1, Mcl-1, and Beclin-1, alongside their implications in apoptosis and cell survival mechanisms. The data includes counts, pattern variations, and potential interactions within the family, contributing to a broader understanding of cell death regulation in health and disease.

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Comprehensive Analysis of Bcl-2 Family Gene Patterns: Mer Size Distribution and Functionality

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  1. Tq patterns Ad patterns UNI60 12-mer (1,236,424) 12-mer (3,894,253) 1,231,877 4,823 3,866,990 1,448 191 7-mer (34,069) 7-mer (34,069) 1,359 17,309 59 17 IPR020728 (43) IPR020728 (43) 26 143 371 0 227 31,900 7 0 8 28,363 28 3 0 2 14 10 1 3 5 2 4 2 6 227 0 0 277 0 0 2 3 1 0 1 1 0 0 1 6 1 2 0 8 13-mer (12,729) 13-mer (50,712) 1,601 4,473 11,002 32,653 9-mer (10,430) 9-mer (10,430) 8,274 5,202 36 255 61 26 Bcl-2 family Bcl-2 (x2) Bcl2l1 (x2) Bcl2l2 (x2) Mcl-1 (x6) Bcl2l10 Bcl2a1 (x2) Ced-9 (x2) Buffy (x3) Debcl (x3) Bax Bak (x6) Bcl2l12 (x3) Bcl2l13 (x4) Bcl2l14 (x2) Bid Bmf M (x6) Apol1 (x6) Apol6 (x9) Atg12 (x2) Beclin-1 (x7) Bnip1 (x10) Bnip2 (x2) Bnip3 (x3) Bnip3L (x2) Clusterin (x8) Cullin-7 (x14) E 12-mer (22) 12-mer (254) Bcl2l15 Beclin-1 Bnip3 Mcf (x3) Cullin-7 Mule (x2) Rad9a Cullin-7 Cullin-7 Bcl2l15 Beclin-1 7-mer (9) 7-mer (14) Bid Mcl-1 Mcl-1 IPR020728 (8) IPR020728 (8) Mule Bim Bok Bok Rad9a Spike Rad9a Spike Bim Bid Hrk Bax Bik Hrk Bax Bik Erbb2 (x10) Erbb4 (x12) Map-1 (x5) Mcf(x34) Mule (x43) Rad9a (x6) Rad9sp (x4) Soul Sphk2 (x3) Spike (x2) Tg2 Ynl305cp (x2) Bcl-xL Bcl-xL Bak Bak Bcl-2 Bcl-2 Bad Noxa Bad 13-mer (7) 13-mer (13) Bcl-w Bcl2l14 Bcl-w Bcl2l14 Mule Mcf Bmf Apol1 Apol6 9-mer (16) 9-mer (16) Apol1 Apol6 Noxa Bmf Puma Puma

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