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بسم الله الرحمن الرحيم

بسم الله الرحمن الرحيم. vasculitis. BY Dr.Nesreen Kotb. What Is Vasculitis ?. What is the Causes of Vasculitis ?. Pathogenesis Of Vasculitis. T Cell mediated . Immune complex mediated Antibodies to antigens that are integral components of vessel wall . ANCA associated vasculitis.

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بسم الله الرحمن الرحيم

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  1. بسم الله الرحمن الرحيم

  2. vasculitis BY Dr.Nesreen Kotb

  3. What Is Vasculitis ?

  4. What is the Causes of Vasculitis ?

  5. Pathogenesis Of Vasculitis • T Cell mediated . • Immunecomplex mediated Antibodies • to antigensthat are integral components • of vessel wall . • ANCA associated vasculitis .

  6. Symptoms of vasculitis • Fatigue • Weakness • Fever • Abdominal pain • Proteinuria , hematuria , casts • Nerve problems (numbness , weakness) • Skin rash

  7. Classification of Vasculitis

  8. Vasculitis • Large vessel vasculitis • Giant vessel vasculitis • Takayasu vasculitis • Medium sized vessel vasculitis • Polyarteritis nodosa • Kawasaki disease • Small vessel vasculitis • ANCA associated • None ANCA associated

  9. Small vessel vasculitis • None ANCA associated • Immune complex vasculitis • -Henoch Schonlein purpura • -Cryglobulinemic vasculitis • -Lupus vasculitis • -Rheumatoid arthritis • -Good pasture’s syndrome • -Behcet disease • Inflammatory Bowel disease • vasculitis. • Paraneoplastic small vessel • vasculitis • ANCA-associated • Wegener’s granulomatosis • Microscopic polyangiitis • Churg- Strauss syndrome

  10. ِ ANCA associated small vessel vasculitis • Granuloma present • Asthma and eosinophilia • (churg-strauss syndrome) • No eosinophilia • (wegener’s granulomatosis) • No granuloma • Microscopic polyangiitis

  11. Diagnosis Of Vasculitis

  12. Treatment Of Vasculitis

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