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Mastering Aerobic Respiration: From Pyruvate to ATP Synthesis

Dive deep into the process of aerobic respiration, focusing on oxidative decarboxylation of pyruvate, Krebs cycle, NADH, electron transport chain, and the vital role of oxygen. Review the nuances of energy production and the ATP synthesis pathway.

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Mastering Aerobic Respiration: From Pyruvate to ATP Synthesis

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  1. Syllabus Notes 1-19-06 Whee! Seriously, I know that this is hard…. It is the hardest thing we learn. If you believe that I don’t realize that… please know that I realize this is all hard… Oh, and Katie the announcement lady needs a MUTE button.

  2. But first a review: (facts that get lost in the details…) • Respiration breaks down food by stripping the electrons away. • All of the carbons that were in the food poofaway as carbon dioxide. • The goal of respiration is to make ATP (body’s energy). • Aerobic Respiration: requires oxygen (Krebs and Electron chain.) • Anaerobic Respiration: does not require oxygen (fermentation.)

  3. C.3.4 Explain aerobic respiration including oxidative decarboxylation of pyruvate, the Krebs cycle, NadH , the electron transport chain and the role of oxygen. • Oxidative decarboxylation of pyruvate: NAD+ takes electrons away (oxidizes) from pyruvate. One carbon escapes as CO2 (Decarboxylation.) Called the LINK reaction between glycolysis and krebs… • Krebs cycle: where electrons get taken from Acetyl CO-A (Formerly pyruvate)by NAD+ and FAD+ and more decarboxylation occurs. • E.T.Chain: Chemiosmosis occurs! NADH and FADH formed give electrons to oxygen. The H+’s that are released go through ATP synthase to make ATP

  4. One turn of the Krebs cycle yields: • 2 CO2 • 3 NADH, H • 1 FADH • 1 ATP

  5. C.3.5 Explain oxidative phosphorylation. • Oxydative phosphorylation is making ATP by chemiosmosis • Substrate-level phosphorylation is where an enzyme makes ATP (slow gluing of P to ADP) • Substrate-level occurs in Krebs and glycolysis…

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