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GRAPPA Research Funding Initiatives: March 2005 Proposal Assessment and Recommendations

In March 2005, the GRAPPA Steering Committee evaluated applications for research funding to support innovative studies in psoriatic arthritis. A budget of $50,000 was allocated, leading to the establishment of a Research Committee to review 11 proposals totaling $266,000 in funding requests. The committee assessed applications based on relevance, significance, innovation, scientific quality, and the applicants' capabilities. Recommended funding included full support for the highest-rated application and partial funding for four others to ensure equitable distribution among all competitive proposals.

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GRAPPA Research Funding Initiatives: March 2005 Proposal Assessment and Recommendations

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  1. GRAPPA research committee Philip Helliwell

  2. History • Steering committee in March 2005 received an application for funds to support a research project • No mechanism to address this despite one of main aims of GRAPPA • Research committee established to receive and assess applications for funding • Identified 2 dermatologists and 2 rheumatologists • Call for proposals with short (3 weeks) closing date • 2005 budget identified as 50K dollars

  3. Research committee • Chair • Philip Helliwell • Rheumatologists • Peter Nash • Eric Ruderman • Dermatologists • Richard Langley • Alan Menter

  4. Proposals • 11 proposals received • Total amount of funding requested 266K • Proposals assessed in terms of • relevance to GRAPPA (filter question) • significance and innovation (0-7) • scientific quality (0-7) • ability and track record of applicants/site to conduct research project (0-7)

  5. Scores

  6. Scores including PSH evaluation

  7. Application # 1 Lubrano and colleagues, Italy: Validity of the Modified Stoke Ankylosing Spondylitis Spine Score (M-SASSS) and of the Bath Ankylosing Spondylitis Radiology Index (BASRI) for the radiological assessment of axial involvement in Psoriatic Arthritis. 10,000 dollars

  8. Application # 2 Stamm and colleagues, Vienna: Measures Associated with Patient Reported Outcomes in Psoriatic Arthritis. Two part study: Part A qualitative, Part B quantitative Some overlap with study of Will Taylor 49,512 dollars

  9. Application # 3 (joint 3rd) Helliwell et al. (Leeds): Validation of assessment tools for dactylitis and enthesitis in Psoriatic arthritis with MRI correlation. 26,600 dollars

  10. Application # 4 (joint 3rd) Boehncke Frankfurt, Germany: Impact of psoriasis on coronary artery calcification 15,000 dollars

  11. Application # 5 (close 4th) Lories/McGonagle Leuven/Leeds: Activated molecular signaling pathways in mesenchymal cells in psoriatic arthritis 12,500 dollars

  12. Recommendations • Fully fund first application • Part fund the next 4, as all received closely similar scores • This results in the (equitable) distribution of 10K dollars to each of the first five applications

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