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Understanding Rheumatoid Arthritis: Pathogenesis, Diagnosis, and Treatment Approaches

Rheumatoid arthritis (RA) is a chronic inflammatory disorder characterized by morning stiffness lasting over 1 hour and symmetric arthritis in hand joints. Key diagnostic criteria include the presence of rheumatoid nodules and radiological changes. The condition can also affect various body systems, such as ocular, cardiac, and neurological. Treatment options incorporate non-steroidal anti-inflammatory drugs (NSAIDs), steroids, and disease-modifying antirheumatic drugs (DMARDs) like methotrexate and hydroxychloroquine. Early diagnosis and management are essential for improving patient outcomes.

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Understanding Rheumatoid Arthritis: Pathogenesis, Diagnosis, and Treatment Approaches

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Presentation Transcript

  1. ????........

  2. Pathogenesis

  3. Diagnostic Criteria Morning stiffness > 1 hr Arthritis of 3 joint areas Arthritis of hand joints Symmetric arthritis Rheumatoid nodules Rheumatoid factor Radiological changes

  4. Articular manifestation

  5. Rheumatoid nodules

  6. Ocular manifestation

  7. Other system Blood Lymphatics Cardiac Neurological

  8. Radiologocal Rheumatoid factor Hematological Others Investigations

  9. Acute inflammation Rest NSAIDS Steroids

  10. DMARDS Methotrexate Hydroxychloroquine Sulfasalazine

  11. Immunosuppresants Leflunamide

  12. Synovectomy

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