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Outcome after Surgical Resections of (recurrent) Chest Wall Sarcomas

Outcome after Surgical Resections of (recurrent) Chest Wall Sarcomas. Is it worthwhile?. Michael Wouters Bert van Geel Lotte Nieuwenhuis Harm van Tinteren Cees Verhoef Houke Klomp Frits van Coevorden. Resections for Chest Wall Sarcoma Background. Sarcomas

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Outcome after Surgical Resections of (recurrent) Chest Wall Sarcomas

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  1. Outcome after Surgical Resectionsof(recurrent) Chest Wall Sarcomas Is it worthwhile? Michael Wouters Bert van Geel Lotte Nieuwenhuis Harm van Tinteren Cees Verhoef Houke Klomp Frits van Coevorden

  2. Resections for Chest Wall SarcomaBackground Sarcomas • 1 % of all malignancies in adults • 10-15% arise in the chest wall • best controlled bywide (full-thickness) chest wall resections • neo-(adjuvant) radio- or chemotherapy

  3. Resections for Chest Wall SarcomaBackground / Literature

  4. Resections for Chest Wall SarcomaBackground / Literature

  5. Resections for Chest Wall sarcomaObjective To evaluate: - morbidity, mortality and (disease-free) survival - outcome for primary and recurrent sarcomas of the chest wall

  6. Resections for Chest Wall sarcomaMethods • retrospective study • 2 tertiary referral centers in the Netherlands • 1980 – 2006 • any sarcoma involving: • Ribs • Sternum • Costo-vertebral junction • Vertebral body • full-thickness Chest Wall resection

  7. Resections for Chest Wall sarcomaFull-thickness Chest Wall resection

  8. Resection of Chest Wall sarcomaPatients median follow-up time: 74 months

  9. Resections of Chest Wall sarcomaResults / Patient & Tumor characteristics

  10. Resections of Chest Wall sarcomaResults / Patient & Tumor characteristics

  11. Resections of Chest Wall sarcomaResults / Treatment characteristics

  12. Resections of Chest Wall sarcomaResults / Outcome / Morbidity

  13. Resections of Chest Wall sarcomaResults / Outcome

  14. Resection of Chest Wall sarcomaResults / Outcome / DFS vs OS DFS OS

  15. Resection of Chest Wall sarcomaResults / Outcome / Recurrences

  16. Resection of Chest Wall sarcomaResults / Outcome / Recurrences

  17. Resection of Chest Wall sarcomaResults / Outcome / Recurrences

  18. Resections for Chest Wall SarcomaDiscussion • Primary and Recurrent Chest Wall sarcomas have different recurrence patterns. • This selection of locally recurrent Chest Wall sarcomas has less tendency to metastasize.

  19. Resections for Chest Wall SarcomaConclusions • Safe and effective procedure, even in locally recurrent sarcomas • 5-year survival after resection of recurrent chest wall sarcomas is ‘worthwhile’! • Recurrent chest wall sarcomas should be resected if technically possible.

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