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Why Bother?. Optimum treatment of lipids helps in the primary
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1. HYPERLIPIDEMIA
Brian V. Reamy, MD, Colonel, USAF, MC
Chair – Department of Family Medicine
Uniformed Services University
2. Why Bother? Optimum treatment of lipids helps in the primary & secondary prevention of ASCVD; still our nation’s #1 killer
3. Why Bother? ASCVD has been #1 cause of death every year since 1900 with exception of 1918.
50% of CVD diagnoses and 15% of CVD deaths are in patients < 65 years of age
Many young adults have 2 or more risk factors that go unrecognized and untreated.
HUGE opportunity to prevent disease!!
4. NCEP/ATP III – 15 May 2001 www.nhlbi.nih.gov
LDL goals lowered
Raised acceptable HDL to 40
Lowered TG goal to 150
Risk Factor assessment enhanced with the 10-yr Framingham risk calculator
Added the Metabolic Syndrome to Tx
5. NCEP/ATP III – 9 Steps Step 1: Obtain, complete & fasting lipids.
Interpret: LDL < 100mg/dl optimal
LDL 100-129 near optimal
LDL 130-159 borderline high
LDL 160-189 high
LDL >190 very high
(mg/dl x 0.0259mmol/l = SI units)
6. NCEP/ATP III Step 2: Identify if patient has CAD or equivalent (PAD, DM, AAA, Carotid)
Step 3: Risk factor assessment (HTN, FHx, Tob, Age & Sex, HDL<40 or >60)
Step 4: If 2 or more risk factors; do Framingham 10-yr risk assessment.
7. Framingham Ten Year Risk