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Neurovegetative Regulationen Einf hrung

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Neurovegetative Regulationen Einf hrung

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    1. Neurovegetative Regulationen (Einführung) Gábor Petheo

    2. Homöostatische Steuerungszentren

    3. Neurovegetative Regulationen (Zentrum)

    4. Neurovegetative Steureungszentren

    5. Beispiel: Osmoregilation in der Ratte

    6. Stress-Physiologie Stressreaktion

    7. Historie János Selye: Unterschiedliche schädigende Eingriffe lösen ähnliche Reaktionen aus Walter B. Cannon: Extrem gefährliche Situationen führen zu „fight-or-flight” Antwort

    8. Definition Ein Zustand, in dem Homöostase im Gefahr ist

    9. Beispiele für Stressoren (Stressreizen) Kalt/Hitze Hypoglikemie Hipolvolemie/Hypotonie Hyperkapnie/Hypoxie/Acidose Schmerz, Verletzung, Infektion Physische Belastung Psychische Belastung …usw.

    10. Hormonale Antwort The Locus coeruleus, also spelled locus caeruleus, is a nucleus in the brain stem involved with physiological responses to stress andpanic. It was discovered in the 1700s by Félix Vicq-d'Azyr. he locus coeruleus is responsible for mediating many of the sympathetic effects during stress. The locus coeruleus is activated by stress, and will respond by increasing norepinephrinesecretion, which in turn will alter cognitive function (through the prefrontal cortex), increase motivation (through nucleus accumbens), activate the hypothalamic-pituitary-adrenal axis, and increase the sympathetic discharge/inhibit parasympathetic tone (through the brainstem). Specific to the activation of the hypothalamo-pituitary adrenal axis, norepinephrine will stimulate the secretion of corticotropin-releasing factor from the hypothalamus, which induces adrenocorticotropic hormone release from the anterior pituitary and subsequent cortisol synthesis in theadrenal glands. Norepinephrine released from locus coeruleus will feedback to inhibit its production, and corticotropin-releasing hormone will feedback to inhibit its production, while positively feeding to the locus coeruleus to increase norepinephrine production The Locus coeruleus, also spelled locus caeruleus, is a nucleus in the brain stem involved with physiological responses to stress andpanic. It was discovered in the 1700s by Félix Vicq-d'Azyr. he locus coeruleus is responsible for mediating many of the sympathetic effects during stress. The locus coeruleus is activated by stress, and will respond by increasing norepinephrinesecretion, which in turn will alter cognitive function (through the prefrontal cortex), increase motivation (through nucleus accumbens), activate the hypothalamic-pituitary-adrenal axis, and increase the sympathetic discharge/inhibit parasympathetic tone (through the brainstem). Specific to the activation of the hypothalamo-pituitary adrenal axis, norepinephrine will stimulate the secretion of corticotropin-releasing factor from the hypothalamus, which induces adrenocorticotropic hormone release from the anterior pituitary and subsequent cortisol synthesis in theadrenal glands. Norepinephrine released from locus coeruleus will feedback to inhibit its production, and corticotropin-releasing hormone will feedback to inhibit its production, while positively feeding to the locus coeruleus to increase norepinephrine production

    11. Zeitmuster Sekunden: Katekolamine/CRH/ACTH ? Minuten: Kortsiol ? (+Glukagon und GH ?) Stunden: Wirkungen von erhöhtem Kortisolspiegel

    12. Zusammenfassunng

    13. Sinne hinter der Stressantwort Maximierung der Überlebenschance Begrenzung der Antworten (stark erhöhte Kortisolspiegel)?

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