1 / 2

EXCELLENT Trial

EXCELLENT Trial. The Randomized Comparison of Six-Month versus 12-Month Duration of Dual Antiplatelet Therapy after Implantation of DES: From A Comparison of EES versus SES for Coronary Revascularization (EXCELLENT) Trial. Study Design Randomized Prospective Open -label Noninferiority.

hyatt-dotson
Télécharger la présentation

EXCELLENT Trial

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. EXCELLENT Trial The Randomized Comparison of Six-Month versus 12-Month Duration of Dual Antiplatelet Therapy after Implantation of DES: From A Comparison of EES versus SES for Coronary Revascularization (EXCELLENT) Trial Study Design • Randomized • Prospective • Open-label • Noninferiority Subject Characteristics • Mean age 63 years • One-third women • About 40% diabetic • >99% on aspirin and clopidogerel; >80% on statins; >50% on beta blockers; about 33% on ACE inhibitors Primary Endpoint • Target vessel failure (TVF) at 12 months

  2. EXCELLENT Trial Results • No significant difference in TVF at 12 months • p=0.43 (superiority) • p=0.0031 (noninferiority) • Significant association (p<0.001) between the presence of diabetes and less favorable results with 6 months of dual antiplatelet therapy (p=0.005) Conclusion More data are needed from larger appropriately powered trials before any changes to clinical practice can be recommended.

More Related