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I/I max PowerPoint Presentation

I/I max

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I/I max

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  1. I/Imax I/Imax Membrane Voltage (mV) B A Indomethacin + b-BuTX (n = 11) 10 pM b-BuTX (n = 14) 10 µM Indomethacin (n = 10) Control (n = 12) Membrane Voltage (mV) D C b-BuTX + indomethacin b-BuTX + indomethacin b-BuTX + indomethacin b-BuTX + indomethacin indomethacin indomethacin indomethacin indomethacin control control control control b-BuTX b-BuTX b-BuTX b-BuTX 0 0 0 0 11 11 11 11 14 10 14 10 14 10 14 10 7 7 12 12 -1 -5 -10 -10 Max. current potential (mV) Activation threshold (mV) -10 -2 -20 -20 -3 -15 -30 -30 -20 -4 -40 -40 -5 -25 -30 -50 -50 E F V1/2 (mV) Slope factor -6 *** *** * * * *