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Chapter 15 The Chromosomal Basis of Inheritance

Chapter 15 The Chromosomal Basis of Inheritance. Timeline. Sutton. Morgan. Fruit Fly. Reasons. Genetic Symbols. Examples. Recessive mutation: w = white eyes w+ = red eyes Dominant Mutation Cy = Curly wings Cy+ = Normal wings. Morgan Observed:. Morgan crossed.

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Chapter 15 The Chromosomal Basis of Inheritance

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  1. Chapter 15 The Chromosomal Basis of Inheritance

  2. Timeline

  3. Sutton

  4. Morgan

  5. Fruit Fly

  6. Reasons

  7. Genetic Symbols

  8. Examples • Recessive mutation: • w = white eyes • w+ = red eyes • Dominant Mutation • Cy = Curly wings • Cy+ = Normal wings

  9. Morgan Observed:

  10. Morgan crossed

  11. The F1 offspring: • All had red eyes. • This suggests that white eyes is a genetic _________?

  12. F1 X F1 = F2

  13. Morgan discovered:

  14. Fruit Fly Chromosomes

  15. Morgan Discovered

  16. Linked Genes

  17. Body Color and Wing type

  18. Example b+b vg+vg X bb vgvg (b+ linked to vg+) (b linked to vg) If unlinked: 1:1:1:1 ratio. If linked: ratio will be altered.

  19. Crossing-Over

  20. If Genes are Linked:

  21. Linkage Strength

  22. Genetic Maps

  23. Comment - only good for genes that are within 50 map units of each other. Why?

  24. Genetic Maps

  25. Sex Linkage in Biology

  26. Chromosomal Basis of Sex in Humans

  27. Human Chromosome Sex

  28. SRY

  29. Sex Linkage

  30. Males

  31. X-linked Disorders

  32. Samples of X-linked patterns:

  33. X-linked Patterns

  34. Comment • Watch how questions with sex linkage are phrased: • Chance of children? • Chance of males?

  35. Can Females be color-blind?

  36. Y-linkage

  37. Sex Limited Traits

  38. Sex Influenced Traits

  39. Baldness

  40. Barr Body

  41. Lyon Hypothesis

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