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Analysis of Total Reports and Deaths Related to Transfusions (1996-2009) in the UK

This report provides a comprehensive analysis of transfusion-related cases reported in the UK from 1996 to 2009. It evaluates total reports and deaths attributable to transfusions, including specific cases of acute transfusion reactions and other serious events like TRALI and Post Transfusion Purpura. The analysis highlights trends, rates of inappropriate transfusions, and errors in handling and storage. It includes data segmented by reporting organisation and details comparisons between adult and paediatric cases, offering valuable insights for improving transfusion safety practices.

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Analysis of Total Reports and Deaths Related to Transfusions (1996-2009) in the UK

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Presentation Transcript

  1. Key slides from the 2009 SHOT Report

  2. Total reports and total deaths definitely due to transfusion 1996 - 2009

  3. Number of reports sent by reporting organisation in the UK 2006 - 2009

  4. Mean number of reports per reporting organisation by RTC

  5. SHOT cases 2009 n = 1279

  6. Cumulative SHOT cases 1996 – 2009 n = 6653

  7. Comparison of report types 1996 – 2009

  8. IBCT cases 1996 – 2009 showing ABO-incompatible transfusions

  9. Cases of inappropriate and unnecessary transfusion 1996 - 2009

  10. Handling and storage error cases 1996 - 2009

  11. Anti-D cases 1996 - 2009

  12. Acute transfusion reaction cases 1996 - 2009

  13. Reaction by component type 2009 (Excluding 6 reactions that could not be attributed to a particular component)

  14. Haemolytic transfusion reaction cases 1996 - 2009

  15. Interval between administration of implicated transfusion and signs or symptoms of DHTR

  16. TRALI cases received and categorised 2009

  17. TRALI cases with concordant door antibody in FFP or platelets 2003 - 2009

  18. Deaths at least possibly due to TRALI and suspected TRALI cases 1996 - 2009

  19. TRALI cases by year of transfusion 1996 - 2009

  20. Number of confirmed cases of Post Transfusion Purpura 1996 - 2009

  21. Number of cases of TA-GvHD 1996 - 2009

  22. Number of bacterial TTI cases by year and component type (Scotland included from 10/1998)

  23. Number of viral and parasitic TTI cases by year and infection type (Scotland included from 10/1998)

  24. Number of Paediatric cases in each SHOT category For the error report categories, the proportion of ‘paediatric-related’ cases is also shown

  25. Acute transfusion reactions – comparison between adult and paediatric reports

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