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Improving Adherence to Treatment in Chronic Diseases: Insights from Allergology and Respiratory Medicine

Non-adherence to prescribed treatments is a significant barrier to achieving optimal clinical outcomes, with up to 50% of patients in developed countries failing to utilize medications as recommended. This issue is particularly prevalent among those with chronic conditions such as asthma and allergic rhinitis. Factors influencing adherence include patient cognition, satisfaction with treatment, drug schedules, and the patient-physician relationship. Through better understanding and addressing these barriers, we can improve treatment adherence and patient quality of life.

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Improving Adherence to Treatment in Chronic Diseases: Insights from Allergology and Respiratory Medicine

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  1. Adherence to treatment: How can it be improved? Non-Adherent patient Fulvio Braido Allergology & RespiratoryDiseases University of Genoa

  2. Factor influencing the clinical outcomes of therapy Thorsson & Geller Respiratory Medicine 2005; 99: 836-849

  3. The extent of Non-Adherence WHO report 50% of patients from developed countries with chronic disease do not use their medications as reccommended.

  4. 971 ptz – 12 countries ECRHS-1 (1990-1994) – ECRHS-2 (1998-2002) Adherent subjects in ECRHS-1 543 Non Adherent subjects in ERCHS-1 428 Adherence in ECRH-2 53.4% Nordic 67.6% Mediterranean 76.4.0% Continental 56.1% Extraeuropean areas Net change in adherence -2% +7.5% +15.0% +19.8%

  5. Disease Cognition Patient Satisfaction Drug Treatment Schedule Inhaler Clinical effects Side effects Patient-Physician Relationship Patient Behaviour Effectiveness = Efficacy X Adherence

  6. J Investig Allergol Clin Immunol 2006 Vol. 16(4):218-223

  7. The concerns about the adverse effects of ICS, is not necessarly related to actual experience, but rather to beliefs about the link between regular use and dependency or other perceived side effects.

  8. Barriers to Adherence Osterberg L. & Blasche T. N.E.J.M. 4 August 2005

  9. Allergic Rhinitis and Asthma ad hoc survey: Clinical and Psychological perspectives F. Braido, I. Baiardini, S. Brandi, A. Porcu, G.W. Canonica Allergy and Respiratory Diseases, DIMI, Genoa University, Genoa, Italy 504 asthmatic patients 27.8% of asthmatic patients experience three or less rhinitic symptoms, 41% from 4 to 6 symptoms, 31.2 % more than 6 symptoms. These symptoms deeply interfere with daily life causing sleep problems (87.3%), lack of concentration (78.9%), difficulties in spare time (71.8%) and sport (71.7%). Rhinitis symptoms are responsible of the worsening of asthma, with an increase of dyspnoea (86.3%), cough (73.9%) wheezing (59%).

  10. Improving Asthma Control Study (IMPACT) – post hoc analisys

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