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Implementing a Discovery Compound Annotation Service for Pharmaceutical Efficiency

This project aims to develop a comprehensive Discovery Compound Annotation Service to enhance pharmaceutical efficiency. By providing a legal and compliant database of annotations for discovery compounds, the service will improve communication among research teams and ensure adherence to legal standards. The anticipated timelines for crucial phases include securing funding, building the database, and rolling out the service across the industry. The estimated value of successful implementation is significant, with potential cost savings in both process efficiency and compound management.

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Implementing a Discovery Compound Annotation Service for Pharmaceutical Efficiency

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  1. High Level Implementation Timeline • Business Case • Unmet Need • Value Proposition Discovery Compound Annotation Service • Projected Shared Project Costs ~$xxx,xxxx[Project Analyst, meetings, socialisation, service implementation] • Estimated value for the industry of implementing this project is TBD • Improved models will provide savings in terms of number of compounds made and reduced project timescales • Pharmaceutical companies generate compounds and progress them through Lead Identification and Lead Optimization processes. • Oftentimes, discovery scientists desire to label or annotate specific compounds with observations made during these processes for purposes of sharing with team members. • Annotations on compounds, if persisted in databases, are discoverable and subject to legal scrutiny (i.e., our lawyers want to control the vocabulary). • Create a database of allowed (and/or disallowed) terms to be used as annotations or labels on discovery compounds compiled from a cross-pharma analysis. • Make database available to commercial companies and research groups for inclusion into externally hosted or in-house services. • Provide discovery relevant and legally compliant annotations. Discovery Compound Annotation Service Available Workstream Start Project Funding Available 1 At-Risk Funding Agreed Q3 - 14 Q4 - 14 Q2 - 15 Q4 - 15

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