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Colloid An Introduction

Colloid An Introduction. Kausar Ahmad Kulliyyah of Pharmacy http://staff.iiu.edu.my/akausar. Contents. Colloidal System. Particle size below 1 m m High specific surface area Discrete particles dispersed in a different medium. Types of Colloids. Classification Based on Size.

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Colloid An Introduction

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  1. Colloid An Introduction Kausar Ahmad Kulliyyah of Pharmacy http://staff.iiu.edu.my/akausar Physical Pharmacy 2

  2. Contents Physical Pharmacy 2

  3. Colloidal System • Particle size below 1 mm • High specific surface area • Discrete particles dispersed in a different medium Physical Pharmacy 2

  4. Types of Colloids Physical Pharmacy 2

  5. Classification Based on Size Physical Pharmacy 2

  6. Classification of dispersed systems Physical Pharmacy 2

  7. Colloidal Phenomena Physical Pharmacy 2

  8. Pharmaceutical suspensions Physical Pharmacy 2

  9. Preparing a Dispersion Physical Pharmacy 2

  10. Properties of dispersing agents END OF LECTURE 1 OF 2 Physical Pharmacy 2

  11. Pharmaceutical Emulsions Physical Pharmacy 2

  12. Emulsification emulsifier homogeniser OIL WATER Physical Pharmacy 2

  13. Emulsification Factors Physical Pharmacy 2

  14. Types of Emulsions Physical Pharmacy 2

  15. Nanoemulsion and Microemulsion Physical Pharmacy 2

  16. Methods of Preparation Physical Pharmacy 2

  17. Multiple Emulsion Physical Pharmacy 2

  18. Example of w/o/w emulsion for drug delivery by intra-muscular route Physical Pharmacy 2

  19. Multiple Emulsion for PharmaceuticalsExamples Sandostatin LARTM Depot • Novartis (hypothalamic hormones analogue) • Control of hypersecretion at the site of the tumour where hormone overproduction starts Human NutropinTM Depot • Alkermes/Genentech (human insulin suspension) • somatropin (rDNA origin) for injectable suspension • long-acting dosage form of recombinant human growth hormone (rhGH). Physical Pharmacy 2

  20. Multiple emulsion Pharmaceutical Problems Physical Pharmacy 2

  21. References PC Hiemenz & Raj Rajagopalan, Principles of Colloid and Surface Chemistry, Marcel Dekker, New York (1997) HA Lieberman, MM Rieger & GS Banker, Pharmaceutical Dosage Forms: Disperse Systems Volume 1, Marcel Dekker, New York (1996) F Nielloud & G Marti-Mestres, Pharmaceutical Emulsions and Suspensions, Marcel Dekker, New York (2000) J Kreuter (ed.), Colloidal Drug Delivery Systems, Marcel Dekker, New York (1994) Physical Pharmacy 2

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