Comparative Analysis of Serum Responses in Human, Rat, and Goat Samples
This study evaluates the optical density (OD) readings at 405 nm of serum samples from humans, rats, and goats. The data includes log10 dilutions of antigens, facilitating comparisons in antibody responses across species. With detailed assessments showing variations in serum responses at different dilutions, the findings highlight the potential differences in immunological profiles among these mammals. This analysis contributes to understanding interspecies variation in serum antibody responses, which can be important for translational research and vaccine development.
Comparative Analysis of Serum Responses in Human, Rat, and Goat Samples
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Presentation Transcript
P1 P1 P1 P1 P1 P1 P2 P2 P2 P2 P2 P2 N N N N N N A. Human sera S S S S S S 0.25 0.6 NSs N 0.5 0.2 0.4 0.15 OD 405 nm OD 405 nm 0.3 0.1 0.2 0.05 0.1 0 0 1.0 1.5 2.0 2.5 3.0 3.5 4.0 4.5 1.0 1.5 2.0 2.5 3.0 3.5 4.0 4.5 Log10 dilution of antigen Log10 dilution of antigen B. Rat sera 1.2 0.8 NSs 0.7 N 1.0 0.6 0.8 0.5 OD 405 nm OD 405 nm 0.6 0.4 0.3 0.4 0.2 0.2 0.1 0 0 1.0 1.5 2.0 2.5 3.0 3.5 4.0 4.5 1.0 1.5 2.0 2.5 3.0 3.5 4.0 4.5 Log10 dilution of antigen Log10 dilution of antigen C. Goat sera 0.8 1.2 0.7 NSs 1.0 N 0.6 0.8 0.5 OD 405 nm OD 405 nm 0.4 0.6 0.3 0.4 0.2 0.2 0.1 0 0 1.0 1.5 2.0 2.5 3.0 3.5 4.0 4.5 1.0 1.5 2.0 2.5 3.0 3.5 4.0 4.5 Log10 dilution of antigen Log10 dilution of antigen
