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Figure 1. RYR1. Ca 2+ channel domain. 1000. 2000. 3000. 4000. 5000. COOH. NH 2. DHPR. IP 3 R. E4032. IP 3 -binding domain. Ca 2+ channel domain. 1000. 2000. NH 2. COOH. SII. SI. E2100. SII-. Type 1. Type 2. Type 3. Figure 2. A. 1000. 2000. IP 3 -binding domain.

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  1. Figure 1 RYR1 Ca2+ channel domain 1000 2000 3000 4000 5000 COOH NH2 DHPR IP3R E4032 IP3-binding domain Ca2+ channel domain 1000 2000 NH2 COOH SII SI E2100 SII- Type 1 Type 2 Type 3

  2. Figure 2 A 1000 2000 IP3-binding domain Ca2+ channel domain NH2 COOH B W1577A IP3-binding domain 1 600 1499 1649 [32] [99] [57] [58] and data not shown [18]

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