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A. L. L. Elastin degradation score. 4. 3. 2. L. L. 1. 0. Sham. P. rTM. B. L. L. SMC content score. 4. 3. 2. 1. L. L. 0. Sham. P. rTM.

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Sham

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  1. A L L Elastin degradation score 4 3 2 L L 1 0 Sham P rTM B L L SMC content score 4 3 2 1 L L 0 Sham P rTM SUPPLEMENTARY FIGURE 5. Treatment with rTMD123 preserves elastin integrity and SMCs in the aortic wall 28 days after AAA induction. A, medial elastin degradation (n=6). Elastin degradation grading scales (4 grades) by VVG staining are indicated in right panels (Blue arrows indicating disrupted elastic lamella). B, SMC content (n=6). SMC content grading scales (4 grades) by α-SMA staining are indicated in right panels. (P=AAA-PBS, rTM=AAA-rTM. **P<0.01, ***P<0.001 compared with sham. #P<0.05 compared with AAA-PBS. L indicates lumen. All scale bars represent 50 μm.)

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