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Cyclodextrin-based Liposome Production

Using dual approach has emerged as a novel plan to tackle the problems of poor aqueous solubility and low rate of dissolution in drug formulation. Therefore, Creative Biostructure combines the cyclodextrins and nanotechnology to develop cyclodextrin-based liposomes that deliver hydrophobic drugs.<br>

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Cyclodextrin-based Liposome Production

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  1. Cyclodextrin-based Liposome Production —Creative Biostructure

  2. Using dual approach has emerged as a novel plan to tackle the problems of poor aqueous solubility and low rate of dissolution in drug formulation. Therefore, Creative Biostructure combines the cyclodextrins and nanotechnology to develop cyclodextrin-based liposomes that deliver hydrophobic drugs.

  3. How Cyclodextrin-Based Liposomes Work Cyclodextrins (CDs) are cyclic oligosaccharides formed from glucopyranose units. With hydrophobic cavity inside and hydrophilic outside, they can form complexes with hydrophobic compounds. The CD/drug inclusion complex provide an alternative approach to encapsulate hydrophobic drugs in the aqueous phase of liposome instead of incorporating them into the phospholipids membrane bilayers. This double-loading technique provides better therapeutic effects in the following aspects.

  4. Cyclodextrin-Based Liposomes Applications • Cyclodextrin-based liposomes is a promising carrier system to preserve volatile and hydrophobic drugs; and provide an access to explore their applications in pharmaceutical, cosmetic and food industry. In addition to liposomes, cyclodextrin-based nanocarriers could be expanded by combination with other carriers like niosomes, nanosponges, micelles, Short Interfering RNA, etc. This complementary carrier system could broaden the scope and accessibility of present and future therapeutic agents.

  5. Creative Biostructure presents our well-developed cyclodextrin-based liposomes technology, which offers the best, customized service to your research:

  6. Various Cyclodextrins Supply: Cyclodextrins and cyclodextrin derivatives are immediately available off-the-shelf; Customized CDs are synthesized to meet different drug properties. • Analytical Services: Encapsulation efficiency (EE%), average particle size (PS), polydispersity index (PDI), zeta potential (ZP), liposomal morphology, drug release studies, and in vivo evaluation. • Cyclodextrin/drug Complexes Preparation Method Development. • Cyclodextrin/drug Loading in Liposomes Method Development. • Pharmaceutical Development • Non-Pharmaceutical Development

  7. Contact Creative Biostructure • Mailing Address: 45-1 Ramsey Road Shirley, NY 11967, USA • Email Address: contact@creative-biostructure.com • Website: http://www.creative-biostructure.com

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