Tat-NR2B9c Treatment Reduces Infarct Size in NHPs with MCAO

Jun 30, 2025

10 likes | 108 Vues

Research on the use of Tat-NR2B9c treatment in non-human primates undergoing MCAO showed significant reduction in infarct volume. Findings, published in Nature, indicate potential neuroprotection in stroke.

Share Presentation

Embed Code

justus

Télécharger la présentation

Tat-NR2B9c Treatment Reduces Infarct Size in NHPs with MCAO

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

Treatment with Tat-NR2B9c attenuates infarct volume in NHPs subjected to MCAO(—)p DJ Cook et al. Nature000, 1-5 (2012) doi:10.1038/nature10841

A D’Hont et al. Nature 000 , 1-5 (2012) doi:10.1038/nature11241

Timing of whole-genome duplications relative to speciation events within representative monocotyledons and eudicotyledons. A D’Hont et al. Nature 000 , 1-5 (2012) doi:10.1038/nature11241.

152 views • 1 slides

K Prüfer et al. Nature 000 , 1-5 (2012) doi:10.1038/nature11128

Segmental duplications and transposon accumulation. K Prüfer et al. Nature 000 , 1-5 (2012) doi:10.1038/nature11128.

105 views • 1 slides

YJ Cui et al . Nature 000 , 1 - 5 (2012) doi:10.1038/nature10897

Impaired trophoblast invasion and spiral artery remodelling in Corin knockout and knockout/transgenic mice. YJ Cui et al . Nature 000 , 1 - 5 (2012) doi:10.1038/nature10897.

198 views • 1 slides

A Kocabas et al. Nature 000 , 1-5 (2012) doi:10.1038/nature11431

Asymmetric AIY excitation modulates the head-bending angle to cause turning. A Kocabas et al. Nature 000 , 1-5 (2012) doi:10.1038/nature11431.

93 views • 1 slides

J Huang et al . Nature 000 , 1 - 5 (2012) doi:10.1038/nature10806

Structure of the menin–MLL1 MBM-LBM –LEDGF IBD ternary complex. J Huang et al . Nature 000 , 1 - 5 (2012) doi:10.1038/nature10806.

206 views • 1 slides

SM Gehrig et al . Nature 000 , 1 - 5 (2012) doi:10.1038/nature10980

Transgenic Hsp72 overexpression increases muscle strength, decreases muscle breakdown and improves diaphragm muscle histological parameters in mdx mice. SM Gehrig et al . Nature 000 , 1 - 5 (2012) doi:10.1038/nature10980.

116 views • 1 slides

AA Mansour et al. Nature 000 , 1-5 (2012) doi:10.1038/nature11272

Downstream effectors of Utx that promote iPSC reprogramming. AA Mansour et al. Nature 000 , 1-5 (2012) doi:10.1038/nature11272.

119 views • 1 slides

M Farago et al. Nature 000 , 1-5 (2012) doi:10.1038/nature11496

Establishment of Ig k allelic choice. M Farago et al. Nature 000 , 1-5 (2012) doi:10.1038/nature11496.

97 views • 1 slides

ER Barry et al. Nature 000 , 1-5 (2012) doi:10.1038/nature 11693

YAP restricts Wnt signalling by blocking DVL nuclear translocation. ER Barry et al. Nature 000 , 1-5 (2012) doi:10.1038/nature 11693.

144 views • 1 slides

BA Buckley et al. Nature 000 , 1-5 (2012) doi:10.1038/nature11352

hrde-1 encodes a nuclear AGO protein that acts in inheriting generations to promote multigenerational germline RNAi inheritance. BA Buckley et al. Nature 000 , 1-5 (2012) doi:10.1038/nature11352.

112 views • 1 slides

M Montagner et al. Nature 000 , 1-5 (2012) doi:10.1038/nature11207

SHARP1 is a suppressor of invasion, migration and metastasis by inhibiting HIFs. M Montagner et al. Nature 000 , 1-5 (2012) doi:10.1038/nature11207.

138 views • 1 slides

T Hino et al . Nature 000 , 1 - 5 (2012) doi:10.1038/nature 10750

Effect of Fab2838 on A2AAR–ligand binding. T Hino et al . Nature 000 , 1 - 5 (2012) doi:10.1038/nature 10750.

143 views • 1 slides

T Hino et al . Nature 000 , 1 - 5 (2012) doi:10.1038/nature 10750

Structure of the A 2A AR–Fab2838 complex. T Hino et al . Nature 000 , 1 - 5 (2012) doi:10.1038/nature 10750.

126 views • 1 slides

DJ Lloyd et al. Nature 000 , 1 - 4 (2013) doi:10.1038/nature 12724

AMG-1694, potency, binding and GKRP–AMG-1694 co-crystal structure. DJ Lloyd et al. Nature 000 , 1 - 4 (2013) doi:10.1038/nature 12724.

110 views • 1 slides

DL Duong et al. Nature 000 , 1-5 (2012) doi:10.1038/nature11562

Observation of graphene grain boundaries (GGBs) after ultraviolet exposure under moisture-rich ambient conditions. DL Duong et al. Nature 000 , 1-5 (2012) doi:10.1038/nature11562.

113 views • 1 slides

DL Duong et al. Nature 000 , 1-5 (2012) doi:10.1038/nature11562

The correlation between GGBs and sheet resistance. DL Duong et al. Nature 000 , 1-5 (2012) doi:10.1038/nature11562.

112 views • 1 slides

W Li et al. Nature 000 , 1-5 (2012) doi:10.1038/nature11435

Generation of ICAI offspring and transgenic mice. W Li et al. Nature 000 , 1-5 (2012) doi:10.1038/nature11435.

139 views • 1 slides

AR Pacheco et al. Nature 000 , 1 - 5 (2012) doi:10.1038/nature11623

The two-component system FusKR of EHEC. AR Pacheco et al. Nature 000 , 1 - 5 (2012) doi:10.1038/nature11623.

112 views • 1 slides

DL Duong et al. Nature 000 , 1-5 (2012) doi:10.1038/nature11562

Height profiles of various topological GGBs, and the oxidation mechanism. DL Duong et al. Nature 000 , 1-5 (2012) doi:10.1038/nature11562.

109 views • 1 slides

J Landsberg et al. Nature 000 , 1-5 (2012) doi:10.1038/nature11538

Proinflammatory mediators directly promote HGF– CDK4(R24C) melanoma cell dedifferentiation leading to impaired recognition by gp100-specific CTLs. J Landsberg et al. Nature 000 , 1-5 (2012) doi:10.1038/nature11538.

117 views • 1 slides

S Francia et al . Nature 000 , 1-5 (2012) doi:10.1038/nature11179

Site-specific DDR focus formation is RNase A sensitive and can be restored by site-specific RNAin aMRN-dependentmanner. S Francia et al . Nature 000 , 1-5 (2012) doi:10.1038/nature11179.

79 views • 1 slides

MA Deardorff et al. Nature 000 , 1-5 (2012) doi:10.1038/nature 11316

HDAC8 mutations in CdLS. MA Deardorff et al. Nature 000 , 1-5 (2012) doi:10.1038/nature 11316.

144 views • 1 slides

More Related