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AHRQ’s Role in Comparative Effectiveness

AHRQ’s Role in Comparative Effectiveness. Carolyn M. Clancy, MD Director Agency for Healthcare Research and Quality Alliance for Health Reform Briefing April 4, 2008. Comparative Effectiveness: Effective Health Care Program.

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AHRQ’s Role in Comparative Effectiveness

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  1. AHRQ’s Role in Comparative Effectiveness Carolyn M. Clancy, MD Director Agency for Healthcare Research and Quality Alliance for Health Reform Briefing April 4, 2008

  2. Comparative Effectiveness:Effective Health Care Program • To improve the quality, effectiveness, and efficiency of health care delivered through Medicare, Medicaid, and S-CHIP programs. • Focus is on what is known now: ensuring programs benefit from past investments in research and what research gaps are critical to fill • Focus is on clinical effectiveness

  3. Key Program Attributes • Infrastructure • Connected to AHRQ Health IT investments • Builds on AHRQ connections with providers and consumers • Unbiased • Responsive • Trusted

  4. Transparency • Public Comment • Priority areas • Nomination of topics for research • Comment on draft research questions • Comment on draft reports • No “Black Box” • Systematic Reviews include details on review methodology and topic considerations

  5. AHRQ Center for Outcomes & Evidence Grants Contracts Intramural Research

  6. Program Outputs Research Reports Consumer Guides Systematic Reviews

  7. What Have We Learned • Often, there are no clear winners and losers • Need to think of questions years in advance of decision makers asking • It is amazing what we don’t know about common and ubiquitous treatments

  8. AHRQ Comparative Effectiveness Research • The additional funding for comparative effectiveness will help AHRQ generate a wealth of new products and tools: • The number of comparative effectiveness reviews and technical briefs will double • New research initiated will include studies on surgery, prescription drugs, biologics and vaccines for Medicare beneficiaries in priority condition areas • A new series of technical reports will establish a foundation for guiding the evaluation of gene-based test performance • The number of products designed to help patients and clinicians make informed decisions will increase

  9. Emerging Methods in Comparative Effectiveness & Safety • A series of 23 articles by AHRQ researchers on new approaches in comparative effectiveness methods are compiled in a special October edition of Medical Care • A valuable new resource for scientists committed to advancing the comparative effectiveness and safety research • All articles available for free download on AHRQ’s website or from AHRQ’s Clearinghouse (Pub. No. OM07-0085) http://effectivehealthcare.ahrq.gov/reports/med-care-report.cfm

  10. From Research to High-Value Health Care • Increased overlap between researchers / product developers and health care leaders  ‘embed’ findings in clinical strategies, electronic and personal health records • Distributed leadership • Clear path for feedback from care delivery to research enterprise at multiple points • From ‘stand-alone’ registries to those that are are used both locally and regionally / nationally • Transparency in production and use of CE information

  11. http://effectivehealthcare.ahrq.gov “Comparative Effectiveness Research typically will focus on realistic decisions confronting patients and their clinicians in actual practice…. Because of this focus on effectiveness as opposed to efficacy, these investigations will likely rely on both prospective trials and observational data to determine relative value in real-world settings.” IOM Roundtable on Evidence-Based Medicine

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