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usmle. Dr.Danil Hammoudi. OSTEOARTHRITIS IS LEAST LIKELY TO BE ASSOCIATED WITH:. ULCERATIVE COLITIS. OSTEOARTHRITIS ASSOCIATED WITH. GOUT HEMOPHILIA WILSON’S DISEASE EHLERS DALOS SYNDROME. AMBIGOUS GENITALIA. ADRENAL HYPERPLASIA. EYES MUSCLES ABDUCTING EYEBALL. INTERNAL RECTUS.

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  1. usmle Dr.Danil Hammoudi Sinoe Medical Association

  2. OSTEOARTHRITIS IS LEAST LIKELY TO BE ASSOCIATED WITH: • ULCERATIVE COLITIS Sinoe Medical Association

  3. OSTEOARTHRITIS ASSOCIATED WITH • GOUT • HEMOPHILIA • WILSON’S DISEASE • EHLERS DALOS SYNDROME Sinoe Medical Association

  4. AMBIGOUS GENITALIA • ADRENAL HYPERPLASIA Sinoe Medical Association

  5. EYES MUSCLES ABDUCTING EYEBALL • INTERNAL RECTUS Sinoe Medical Association

  6. EXTRINSIC EYE MUSCLES AND ROLE Sinoe Medical Association

  7. EXTERNAL MUSCULATURE OF THE EYE • LEVATOR PALPEBRAE SUPERIORIS MUSCLES OPEN THE UPPER EYELID • ORBICULARIS OCULI, A SPHINCTER LIKE MUSCLE, CLOSE EYELIDS Sinoe Medical Association

  8. INCUBATION PERIOD FOR STAPHYLOCOCCAL FOOD POISONING: • 2 TO 4 HOURS Sinoe Medical Association

  9. KRABBE’S DISEASE • GLOBOID CELL LEUKODYSTROPHY • ONSET IN INFANT WITH RIGIDITY • TERMINAL BLINDNESS • DEFICIENCY OF BETA GALACTOSIDASE • ACCUMULATION OF GALACTOCEREBROSIDE. Sinoe Medical Association

  10. COBALT IS AN ESSENTIAL COMPONENT OF: • CYANOCOBOLAMIN [B12] Sinoe Medical Association

  11. HIRSUTISM ARE ASSOCIATED WITH • ADRENAL TUMOR • HYPOTHYROIDISM • DANAZAL THERAPY • CYCLOSPORINE THERAPY Sinoe Medical Association

  12. INCREASED IN VMA IS USUALLY SEEN IN : • NEUROBLASTOMA • PHEOCHROMOCYTOMA Sinoe Medical Association

  13. LANGHERAN’S CELL HISTIOCYTOSIS CLINICAL FORMS • LETTER SIWE DISEASE • HAND SCHBLIER CHRISTIAN DISEASE • EOSINOPHILIC GRANULOMA • HASHIMOTO PRITZKER DISEASE Sinoe Medical Association

  14. HISTIOCYTOSIS, LETTERER SIWE DISEASE • ONSET IN THE FIRST YEAR • HAVE SEBORRHEIC RASH • OTITIS MEDIA • LYMPHADENOPATHY, PURPURA ANEMIA, • HEPATOSPLENOMEGALY • EXTENSIVE LYTIC SKULL LESION =RAINDROP SKULL • UNKNOWN ETIOLOGY • WORST PROGNOSIS Sinoe Medical Association

  15. HISTIOCYTOSIS X • INTENSE PROLIFERATION OF RETICULOHISTIOCYTIC CELLS • EOSINOPHILIC GRANULOMA • HAND SCHULLER CHRISTIAN DISEASE • LETTER SIWE DISEASE Sinoe Medical Association

  16. EOSINOPHILIC GRANULOMA: EG -60-80% OF HISTIOCYTOSIS X -AGE 5-10 YRS MOST COMMON -BEST PROGNOSISHAND SHULLER-CHRISTIAN DISEASE -AGE 1-3 YRS LETTERER SIWE DISEASE -AGE 0-1YRS -WORST PROGNOSIS : MORTALITY 70%] -=MALIGNANT FORM OF HISTIOCYTOSIS Sinoe Medical Association

  17. HAND SCHUELLER CHRISTIAN DISEASE • 1-3 YRS, • MOST COMMON HISTIOCYTOSIS FORM • SKULL – MANDIBULE LESION SEMILAR EOSINOPHIL GRANULOMAS BUT MORE NUMEROUS • GEOGRAPHIC SKULL “FLOATING TEETH” • ADENOPATHY • HEPATOSPLENOMEGALY • SKIN LESION • DIABETES INSIPIDUS • EXOPHTALMOS • LUNG DISEASE Sinoe Medical Association

  18. LETTERER SIWE DISEASE SYNONYMS • ACUTE DIFFUSIBLE HISTIOCYTOSIS • ACUTE INFANTILE RETICULOENDOTHELIOSIS • ACUTE RETICULOSIS OF INFANCY • GENERALIZED HISTIOCYTOSIS • NON LIPID RETICULOENDOTHELIOSIS Sinoe Medical Association

  19. CURLING ULCER OF THE STOMACH /MARJOLIN OF THE SKIN ARE CAUSES BY: • BURNS Sinoe Medical Association

  20. CEREBROSPINAL FLUID IN VIRAL ENCEPHALITIS SHOWS: • VARIABLE PLEOCYTOSIS • DECREASED SUGAR LEVEL • INCREASED PROTEIN LEVEL Sinoe Medical Association

  21. PRIMARY BILIARY CIRRHOSIS • MORE COMMON IN WOMEN THAN IN MEN • ASSOCIATED WITH PRURITUS, JAUNDICE,XANTHOMATOUS LESIONS • INCREASED ALKALINE PHOSPHATASE AND CHOLESTEROL • MITOCHONDRIAL ANTIBODIES AND INCREASED SERUM IgM. Sinoe Medical Association

  22. SABER SHIN OCCURS MAINLY IN CHILDREN WITH: • CONGENITAL SYPHILIS Sinoe Medical Association

  23. THE MOST COMMON INTRACRANIAL GERM TUMOR • GERMINOMA Sinoe Medical Association

  24. GERMINOMAS • HIGHLY RADIOSENSITIVE Sinoe Medical Association

  25. TYPES OF GLIOMAS • ASTROCYTOMAS • EPENDYNOMAS • GANGLIOMAS • OLIGODENDROGLIOMAS • MIXED GLIOMAS Sinoe Medical Association

  26. CHILDHOOD GLIOMAS • ASTROCYTOMAS • EPENDYMOMAS • GANGLIOGLIOMAS Sinoe Medical Association

  27. GERM CELL TUMORS [CGTs] • GERMINOMAS • TERATOMAS • CHORIOCARCINOMAS • ENDODERMAL SINUS TUMORS • EMBRYONAL CARCINOMAS • MIXED GCTs Sinoe Medical Association

  28. PINEAL PARENCHYMAL TUMORS • PINEOBLASTOMAS • PINEOCYTOMAS Sinoe Medical Association

  29. PINEAL GLIOMAS • ASTROCYTOMAS • EPENDYMOMAS Sinoe Medical Association

  30. PINEAL NEOPLSMS • 5% OF ALL PEDIATRICS BRAIN TUMORS Sinoe Medical Association

  31. OSGOOD SCHLATTER DISEASE USUALLY OCCURS IN CHILDREN AGED • 11 TO 13 YEARS Sinoe Medical Association

  32. OSGOOD SCHLATTER • OSTEOCHONDROSIS • PARTIAL AVULSION OF THE TIBIA TUBEROSITY, WITH NO INVOLVEMENT OF THE TIBIA PHYSIS • COMMON CAUSES CAUSES OF KNEE PAIN IN ADOLESCENT • SWELLING AND TENDERNESS JUST BELOW THE KNEE OVER THE SHIN BONE [TIBIA] • MORE COMMON IN BOYS • 8-13 YEARS GIRLS, 10-15 BOYS • GROWTH SPURT AND MAY AFFECT BOTH KNEES , ENLARGEMENT OF THE TIBIAL TUBERCLE. • GOES AWAY WITH TIME Sinoe Medical Association

  33. RED SCALY WITH A SHARP RAISED BORDER ON THE PERINEUM , THIGHS AND BUTTOCKS ARE SEEN IN TINEA • CRURIS [JOCK ITCH] Sinoe Medical Association

  34. TINEA CRURIS= JOCK ITCH • ANY ITCHING IN THE GROIN RASH IN MEN • WHEN CAUSED BY A FUNGUS = RASH=TINEA CRURIS • CAUSE OF TINEA CRURIS= FUNGUS DERMATOPHYTES=RINGWORM FUNGI • NOT CONTAGIOUS • BILATERAL • DO NOT INCLUDE PENIS AND SCROTUM • MIGRATE TO THE BUTTOCK AND GLUTEAL CLEFT AREA Sinoe Medical Association

  35. DERMATOPHYTES INFECTION IN TINEA CRURI • MICROSPORUM • TRICHOPHYTON • EPIDERMOPHYTON Sinoe Medical Association

  36. THE MOST COMMON CAUSE OF A VIGINITIS IN A 10 YEARS OLD GIRL IS • FOREIGN BODY Sinoe Medical Association

  37. RETINOBLASTOMA • MOST COMMON IN LESS THAN 3 YEARS OF AGE • SHOW WHITE CAT’S EYES REFLEX ON FUNDOSCOPY • ARE AUTOSOMAL DOMINANT • BILATERAL 30% OF CASES • ARE THE MOST INTRAOCULAR TUMOR IN CHILDREN Sinoe Medical Association

  38. RETINOBLASTOMA • LEUKOCORIA [WHITE PUPIL REFLEX] • STRABISMUS • EXOTROPIA • ESOTROPIA • RED PAINFUL EYE • POOR VISION , INFLAMMATION TISSUE AROUND THE EYE • ENLARGED OR DILATATED PUPIL • HETEROCHROMIA • FAILURE TO THRIVE • EXTRA FINGERS OR TOES • MALFORMED EARS • RETARDATION Sinoe Medical Association

  39. NOT A CLINICAL FEATURE OF ANOREXIA NERVOSA • HISTORY OF CHILDHOOD HYPERACTIVITY Sinoe Medical Association

  40. ANOREXIA NERVOSA • AMENORRHEA • BRADYCARDIA • ONSET BEFORE 25 YEARS OF AGE Sinoe Medical Association

  41. CHROMOSOMAL ANALYSIS IS USEFUL IN • TESTICULAR FEMINIZATION • GONADAL DYSGENESIS Sinoe Medical Association

  42. Sinoe Medical Association

  43. DIFFERENTIAL DIAG OF TINEA CRURIS • INTERTRIGO • ERYTHRASMA • SEBORRHEIC DERMATITIS OF THE GROIN • PSORIASIS OF THE GROIN • CANDIDIASIS OF THE GROIN Sinoe Medical Association

  44. SINDING LARSEN JOHANSSON SYNDROME • RESEMBLES OSGOOD SCHLOTTER DISEASE, EXCEPT SYMPTOMS LOCALIZED IN THE INFERIOR POLE OF PATELLA • CHRONIC OVERTENSION OF EXTENSORMECHANISM • PAIN • OSSIFICATION DISTURBANCE • SWELLING • WEAK QUAD • REPETITIVE LOADED KNEE FLEXION ACTIVITIES: • LIGAMENT AVULSION • SOFT TISSUE CALCIFICATION • STRESS FRACTURE Sinoe Medical Association

  45. OSTEOCHONDROSIS • LEGG CALVE PERTHES DISEASES =CAPITAL FEMORAL EPIPHYSIS • KOHLER DISEASE =TARSAL NAVICULAR • OSGOOD SHLATTER DISEASE=TIBIAL TUBEROSITY • SCHEUERMANN DISEASE=VERTEBRAL RING EPIPHYSES • FREIBER INFRACTION =METATARSAL HEAD • SEVER DISEASE = APOPHYSIS OF OS CALCIS • OSTEOCHONDRITIS DISSECANS Sinoe Medical Association

  46. OSTEOCHONDROSIS DISSECANS • SUBCHONDRAL FATIGUE FRACTURE • COMMONLY SEEN IN ADOLESCENT • CAPITELLUM OF THE ELBOW • KNEE [MEDIAL FEMORAL CONDYLE CLOSE TO FOSSA INTERCONDYLARIS] • TALUS • MOUSE= OSTEOCHONDROTIC FRAGMENT • MOUSE BED= SCLEROSED PIT IN ARTICULAR SURFACE Sinoe Medical Association

  47. SEVER DISEASE • OSTEOCHONDROSIS • APOPHYSIS OF THE OS CALCIS [UNDERGOES FRAGMENTATION] Sinoe Medical Association

  48. FREIBERG INFRACTION • OSTEOCHONDROSIS • METATARSALHEAD • 2ND COMMON • 3RD AND 1ST LESS COMMON • INFARCTION OR STRESS FRACTURE • LATE ADOLESCENCE • A END ARTICULAR BECOMES FLATTENED • SMALL OSSICLES MAY FORM AFTER HEALING • DJD IS COMMONLY LATE COMPLICATION Sinoe Medical Association

  49. SCHMORL NODE • CHONDRIFICATION DEFECTS WHERE PERIOSTEAL VESSELS PENETRATE CARTILAGE PLATE OF DISC Sinoe Medical Association

  50. KOHLER DISEASE • OSTEOCHONDROSIS OF TARSAL NAVICULAR Sinoe Medical Association

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