1 / 10

Neuro-Psychiatric Comorbidity among Psoriatic Adolescents

Neuro-Psychiatric Comorbidity among Psoriatic Adolescents. Eran Galili , Aviv Barzilai , Rony Shreberk -Hassidim, Ilan Merdler , Tomm Caspi , Nadav Astman Journal reference: 10.1111/bjd.16031. Introduction What’s already known?.

kedem
Télécharger la présentation

Neuro-Psychiatric Comorbidity among Psoriatic Adolescents

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Neuro-Psychiatric Comorbidity among Psoriatic Adolescents EranGalili, Aviv Barzilai, RonyShreberk-Hassidim, IlanMerdler, TommCaspi, NadavAstman Journal reference: 10.1111/bjd.16031

  2. Introduction What’s already known? • Adultpsoriasis is a risk factor for psychiatric and neurological diseases • Few studies among children, comprising of subjects of mixed age groups (younger than 18 years), have linked psoriasis to anxiety, depression and social disabilities

  3. Methods • Design: A population based cross-sectional study • Database: Army recruits’ medical records • Inclusion criteria: Age 16 to 18 years • Comparisons were made by multivariate analysis adjusted for: • Age, Gender, Country of origin, BMI, Socio-economic status and IQ score • Psoriasis severity definition: • Mild: with limited skin involvement, using topical treatment only • Moderate to severe: with extensive skin area involvement, or treated with phototherapy or systemic therapy

  4. Methods: Assessed Comorbidity CNS, central nervous system; *Consists of: multiple sclerosis, neurodegenerative disease and cerebrovascular accident

  5. Results: Characteristics of study participants * On a scale of 1 (lowest) to 10 (highest)

  6. Results: Comparison of neuro-psychiatric comorbidity between psoriatic and healthy adolescents NS, non-significant; ᵃ Calculated for a subgroup of patients (Psoriasis N=1135, Controls N=265023); **pvalue < 0.01, ***pvalue < 0.001

  7. Results: Influence of psoriasis severity compared to controls ᵃ Calculated for a subgroup of patients (Mild psoriasis N=669, moderate to severe psoriasis N=466 and controls N=265023), univariate analysis; **p value< 0.01, ***p value< 0.001

  8. Discussion What does this study add? • Adolescent psoriasis was found to be associated with migraine and non-migraine headaches, as well as psychological symptoms, including anxiety and impaired social adjustment skills • Neuro-Psychiatric comorbidity was found to be related only to moderate to severe psoriasis

  9. Conclusions • Clinicians should be aware of the collateral impact of psoriasis, especially upon adolescents with moderate to severe disease

  10. Call for correspondence • Why not join the debate on this article through our correspondence section? • Rapid responses should not exceed 350 words, four references and one figure • Further details can be found here: (insert link to author instructions)

More Related