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The epidermal growth factor receptor plays an anabolic role in bone. Osteoscoop - Issue N°202 – September 2011. EGFR. Osteoblast. EGFR ligands. HBEGF. Epigen. Amphiregulin. Epiregulin. Betacellulin. TGF . EGF. EGFR. Osteoblast. EGFR ligands. HBEGF. Epigen. Amphiregulin.
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The epidermal growth factor receptor plays an anabolic role in bone Osteoscoop - Issue N°202 – September 2011
EGFR Osteoblast
EGFR ligands HBEGF Epigen Amphiregulin Epiregulin Betacellulin TGF EGF EGFR Osteoblast
EGFR ligands HBEGF Epigen Amphiregulin Epiregulin Betacellulin TGF EGF EGFR P P Osteoblast
EGFR ligands HBEGF Epigen Amphiregulin Epiregulin Betacellulin TGF EGF EGFR P P Signaling pathways Osteoblast
EGFR ligands HBEGF Epigen Amphiregulin Epiregulin Betacellulin TGF EGF EGFR P P Signaling pathways Osteoblast Reduced bone resorption Increased bone formation Increased bone volume and mineral density