Human Growth Hormone Also known as… HGH or GH Growth Hormone Healing Hormone Anti-aging Hormone Recumbant HGH/synthetic
Chemical NameBrand Names • Norditropin • Jintropin • Zomacton • Ansomone • Tev-Tropin • Fitropin • SOMATROPIN • Nutropin • Hypertropin • Humatrope • Saizen • Serostim • Zorbtive
What does HGH do? • HGH is a hormone that is secreted by the pituitary gland. • Encourages growth, cell production and regeneration. • Commands Various functions: • Stimulates tissue repair • Aids in replacement of cells • Controls brain functions • Manipulates function of various enzymes
Crucial in Development • HGH is crucial in height gains in children/adolescents • Preserves Calcium, while inhibiting bone minerilization • Enhances muscle mass, and protein production • Promotes lipolysis and glucose functions • Stimulates immune system • Preserves youthfulness • Everyone produces HGH, but as the body ages the levels of it drop (Radomski 90).
HGH Cont… • HGH can slow down the aging process, allowing the body to heal more quickly, building their immune system, and reversing signs of aging (Radomski 90). • Prior to 1985, HGH could only be obtained in scarce amounts from the pituitary gland of cadavers (Wadler 70).
History of HGH • 1958: GH excreted from cadavers pituitary glands to sucessfully treat GH deficiency in 17 y.o. boy. • Excreted HGH became known as Cadaver GH • 1960: National Pituitary Agency created to distribute cadaver-gh for children with GH deficiency • Cadaver derived Growth Hormone was only given to children with GH-deficiency • Medication ceased when the child met their average minimal height level for their age. • http://www.somatropin.net/hgh-history.htm
History of HGH….. • Late 70’s: companies begin purchasing Pituitary glands from European hospitals for commercial use • 1985: Cases of Creutzfeldt-Jakob Disease occurs in patients treated with cadaver-GH in the 60’s, the FDA soon ceased distribution • CJD: form of brain damage leading to decreased mental function and movement • 1981: New method is used to create the 1st synthetic GH known as Recombinant HGH www.ncbi.nlm.nih.gov • http://www.somatropin.net/hgh-history.htm
Growth Hormone rapidly decreases after age 30 • In 1990 a study was done, the results led HGH to be known for its astonishing “anti-aging” effects • By the end of the 90’s HGH also became associated with its Weight loss abilities, and positive effects on body composition • In an article HGH was labeled, “fountain of youth in a syringe”, The 1990’s
Schedule III Drug Under the HGH Restriction Act of 2007 classified HGH in any form, as a Schedule III controlled substance. Schedule Rating *Many sports have included HGH as one of their banned substances in their anti-doping poilicies (MLB,NFL, Cycling) http://www.opencongress.org/bill/110-h4911/show
HGH Schedule III • A drug or other substance that has less potential for abuse than those classified as Schedules I or II • It has a currently used medically, and an accepted treatment in the United States • Abusing the drug or substance can lead to moderate to low physical dependence or high psychological dependence WHATS A SCHEDULE iii DRUG?
Physiological Effects HGH does not alone build muscle, but with steroids it could literally make a person build muscle in their sleep • Wrinkle Reduction • Less sagging of skin on face and neck • Firmer Muscles • Less Body Fat • Better Skin (thicker) • Thicker head hair
Psychological Effects • Improved sense of Emotional state • Increased energy • Increased physical stamina • Decreased anxiety • Less tired, can stay up later • Increased stress resistance • Improved assertiveness • Feeling of increase physical power • Improved Self-esteem • Depression improved or eliminated • More Social • Less urge to give verbal retorts
Side Effects: • Cadaver-GH was linked to CJD • Increased hair growth • Edema: Fluid Retention • Arthritis/Joint Pain • Hyperglycemia • Carpal Tunnel, and Hypertension • From excess dosages of HGH EXTREME DOSES (usually in athletes) • Abnormal growth of the hands/feet/face bones • Increased Blood Pressure • Heart Damage
http://www.hghnews.us/about-human-growth-hormone/history-of-growth-hormone/http://www.hghnews.us/about-human-growth-hormone/history-of-growth-hormone/ http://www.hgh.org http://www.hghresearch.net/side-effects-of-hgh.htm http://www.hormoneandlongevitycenter.com/growthhormone/#2 http://www.opencongress.org/bill/110-h4911/show Radomski, Kirk. Bases Loaded. New York: Penguin Group, 2009. http://www.somatropin.net/hgh-history.htm Works CITED Links: