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SMELL AND TASTE. Jeffrey Zhao, Michael Dawkins, Ryan Fischer, Leah Politte, Sarah Mariani, Alexa Stanley. Essential Ideas. Nature of energy transduction, relevant anatomical structures, and specialized pathways in the brain for smell and taste
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SMELL AND TASTE Jeffrey Zhao, Michael Dawkins, Ryan Fischer, Leah Politte, Sarah Mariani, Alexa Stanley
Essential Ideas • Nature of energy transduction, relevant anatomical structures, and specialized pathways in the brain for smell and taste • Common sensory disorders in relation to smell and taste • The basic tastes • Differences between sense of taste, smell, and flavor
Basics of Smell • When you smell something, you are really smelling odor particles • Smell signals are NOT relayed through the thalamus • This suggests smell evolved earlier than other senses • Olfaction is the sense of smell- involves a chain of biochemical events • Humans have around 40 million olfactory receptors that detect up to 10,000 different odors
Basic Steps of Olfaction Step 1: Odors interact with receptor proteins associated with specialized hair (cilia) in the nose Step 2: The stimulated nerve cells associated with these hairs covey information to the brain’s olfactory bulbs (underside of the brain between the frontal lobes) Step 3: In the olfactory bulbs, sensations of smell are realized
Detecting the Odorants • Odor molecules hit the olfactory epithelium- one square inch area of the nasal cavity • Odor molecules stimulate olfactory receptor cells, which are neurons • Olfactory hairs cover the dendrites • When the molecule binds to the receptor cell, the dendrite fires an electrical impulse to the olfactory bulb
Detecting the Odorants (continued) • Supporting cells provide structure to the epithelium, insulate receptor cells, and detoxify chemicals on the epithelium surface • Basal stem cells divide and create new olfactory receptors (regenerate monthly) • Trigeminal nerve fibers in the olfactory epithelium respond to pain • For example, when you breathe in ammonia
Processing the Odorants • Richard Axel and Linda Buck discovered each olfactory receptor only has one type of receptor • Sends signal to a microregion (glomerulus) of the olfactory bulbs • Brain interprets this pattern of signals (called an “odorant pattern”) • Luca Turin proposed an alternative theory • Olfactory sensors respond to quantum vibrations of odors. • Each receptor is not limited to just one type of odorant molecule
Smell in Humans • In humans, smell connected to memory • Certain scents can evoke past memories • Biologically, a survival skill -- helps us locate and detect food • Human sense of smell continues to increase and plateaus at around 8, and decreases with old age • Some research suggests humans may use sexual pheromones and pheromones that help identify family members by smell
Smell in Animals • Used for communication • For example, some insects secrete odorous signals called pheromones to communicate • Pheromones can signal sexual receptivity, danger, territorial boundaries, and food sources • Many animals have two separate olfactory systems • Main olfactory system- detects volatile stimuli • Accessory olfactory system- detects fluid-phase stimuli and most pheromones
Basics of Taste • Taste and smell are very closely related • Gustation is your sense of taste • The 5 Basic Tastes • Sweet • Salty • Sour • Bitter • Umani
Taste Receptors • Taste receptor cells are gathered in taste buds on the top and side of tongue • These receptors cluster in small mucous-membrane projections (papillae) • Sensitivity to taste sensations is a result of papillae density on the tongue
Pathway of Tasting • Specialized nerve “hotline” carries taste messages to brain • A specialized region in the somatosensory cortex (in the parietal lobe) realizes taste • This area is next to the part of the brain that receives touch stimulation from the face
Locating the Tastes • Bitter is in the back of tongue • Sour is on each side of the tongue • Sweet and Salty are towards the front of the tongue • There are not many taste buds in the middle
The Basic Tastes- Bitterness • Most sensitive of the tastes • People with more taste buds for bitter flavors are called supertasters • Supertasters will have distaste for certain foods like broccoli and diet drinks • Survival advantage since poisons are bitter
The Basic Tastes (Continued) Saltiness Sourness The taste that detects acidity The mechanism by which sourness is detected is not fully understood Fruits are the most common group of foods linked to sourness • A taste produced mainly by the presence of sodium ions • Other ions like potassium can also produce a salty taste
The Basic Tastes (Continued) Sweetness Unami Described as the taste that comes with monosodium glutamate (MSG) Appetitive and savory taste Cheese and soy sauce are other examples of unami • Produced by the presence of sugars • Detected by G Protein coupled receptors