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DISEASES OF CORNEA

VIRAL KERATITIS . HERPES SIMPLEX KERATITISHERPES ZOSTER OPTHALMICUS. HERPES SIMPLEX KERATITIS. HSV 1: common viral cause of ocular diseasesHSV 2: genital dis. Rarely can cause ocular manifestations (rarely) such as keratitis

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DISEASES OF CORNEA

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    1. BY: Amany Mahameed DISEASES OF CORNEA

    2. VIRAL KERATITIS HERPES SIMPLEX KERATITIS HERPES ZOSTER OPTHALMICUS

    3. HERPES SIMPLEX KERATITIS HSV 1: common viral cause of ocular diseases HSV 2: genital dis. Rarely can cause ocular manifestations (rarely) such as keratitis & infantile chorioretinitis. HSV Primary infection is usually early in life. Enters a latent period in the trigeminal ganglion, When activated it moves along the sensory part of the N. toward the target epith. causing damage & ulceration. Factors leading to activation :psychiatric dis. , systemic illnesses, immunocompromised pt.

    4. HERPES SIMPLEX KERATITIS Symptoms: -Typically unilateral red eye -Variable degree of pain -Ocular irritation -Tearing -Vision may or may not be affected -Vesicular lid lesions and follicular conjunctivitis

    5. HERPES SIMPLEX KERATITIS Signs: Dendritic corneal ulcer (hallmark sign of HSV infection) Ulcer may heal without scar but may progressed to stromal keratitis Associated with inflammatory infiltration and edema Loss of corneal transparency in more severe presentations. Uveitis and glaucoma may accompany disease

    6. Because the virus invades and compromises the epithelial cells surrounding the ulcer, the leading edges (the so-called "terminal end-bulbs") will stain with rose bengal or lissamine green.

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