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Enhancing Tissue Recovery in Stress Urinary Incontinence with MSC: Insights from K08 Mentor Program

Join Dr. Adonis Hijaz, an expert in Female Pelvic Medicine and Surgery, as he discusses the crucial role of tissue recovery in stress urinary incontinence. This presentation explores the potential mechanisms through which Mesenchymal Stem Cells (MSCs) can enhance recovery. Dr. Hijaz shares his journey through the K08 process, emphasizing the importance of mentorship, clinical productivity, and developing a robust research plan. Learn from his experiences in grant writing and internal reviews that led to successful funding.

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Enhancing Tissue Recovery in Stress Urinary Incontinence with MSC: Insights from K08 Mentor Program

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  1. Professional Skills Program K-Grants For Lunch! Adonis Hijaz, MD Associate Professor Director, Center Female Pelvic Medicine & Surgery Urology Institute, University Hospitals Case Medical Center Case Western Reserve University

  2. Tissue recovery in the pathophysiology of stress urinary incontinence Improve tissue recovery with the use of MSC Determine the potential mechanism through which MSCs potentiate recovery

  3. Mentors Primary Mentors Arnold Caplan, PhD Firouz Daneshgari, MD Secondary Mentors Alan Levine PhD James Liu, MD

  4. Why K08? Passion for research Great research idea Excellent preliminary results Passion for research Clinical Productivity Although essential, they are not enough in this Highly competitive world

  5. What does the K08 provide? Protected time Mentorship Discipline Target These are the additional criteria that are ESSENTIAL For successful career as a Clinician Scientist

  6. Lessons learned Be smart about picking your mentor Authority in field with vast mentorship experience Should share your passion and believe in your capabilities Willing to take on the task during the application and thereafter Yet would be your toughest Critique

  7. Lessons learned Personal level Learn the art/science of grant writing- read successful applications Perform an internal review: your areas of weakness might be opportunities for career development Develop thick skin Research Plan Put your ideas out for critique: I submitted an (R03, R21 with revision) on the concept before embarking on the K08. Use the critiques to improve on your research plans and idea

  8. Surprises The surprise was that I got a fundable score from first submission

  9. Acknowledgment Mentors Arnold Caplan PhD Firouz Daneshgari MD James Liu MD Alan Levine PhD UI Grants team Kerry Grimberg PhD Michael Kavran Laurel Jeffers Claudia Lillibridge Laboratory colleagues Michael Kavran Mingfang Tao MD Guiming Liu MD,PhD Zubeyir Altuntas PhD Nicholas Boncher MD Zhina Sadeghi MD Grants & Contracts office Robin Bissell Colleen Goss Katalin Blankenship

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